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HomeProduct name listD(+)-Ribonic acid gamma-lactone

D(+)-Ribonic acid gamma-lactone

Synonym(s):D(+)-Ribono-1,4-lactone

  • CAS NO.:5336-08-3
  • Empirical Formula: C5H8O5
  • Molecular Weight: 148.11
  • MDL number: MFCD00063241
  • EINECS: 226-256-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-09 21:40:10
D(+)-Ribonic acid gamma-lactone Structural

What is D(+)-Ribonic acid gamma-lactone?

Chemical properties

White Crystalline Solid

The Uses of D(+)-Ribonic acid gamma-lactone

Important chiral synthon

The Uses of D(+)-Ribonic acid gamma-lactone

A sugar lactone as inhibitor of β-galactosidase of E. coli.

The Uses of D(+)-Ribonic acid gamma-lactone

D-ribono-1,4-lactone is a compound useful in organic synthesis.

What are the applications of Application

D-Ribonolactone is a sugar lactone and β-galactosidase inhibitor

Definition

ChEBI: A five-membered form of ribonolactone having D-configuration.

Purification Methods

Purify D-(+)-ribonic acid--lactone by recrystallisation from EtOAc. The tribenzoate has m 54-56o (from AcOH), [] D 25 +27o (c 2.37, Me2NCHO), and the 3,5-O-benzylidene derivative has m 230-231.5o (needles from Me2CO-pet ether) and [] D 25 -177o (CHCl3). [Chen & Joulié J Org Chem 49 2168 1984, Zinner & Voigt J Carbohydr Research 7 38 1968.]

Properties of D(+)-Ribonic acid gamma-lactone

Melting point: 85-87 °C(lit.)
Boiling point: 188.68°C (rough estimate)
alpha  18 º (c=5, H2O)
Density  1.2336 (rough estimate)
refractive index  18 ° (C=1, H2O)
storage temp.  Sealed in dry,Room Temperature
solubility  H2O: 0.1 g/mL, clear
form  Powder
pka 12.10±0.60(Predicted)
color  White to Pale Yellow
optical activity [α]24/D +18°, c = 1 in H2O
Water Solubility  soluble
BRN  82057
Stability: Stable
CAS DataBase Reference 5336-08-3(CAS DataBase Reference)
NIST Chemistry Reference D-(+)-Ribonic acid gamma-lactone(5336-08-3)

Safety information for D(+)-Ribonic acid gamma-lactone

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H314:Skin corrosion/irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P310:Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for D(+)-Ribonic acid gamma-lactone

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