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HomeProduct name listTrigonelline hydrochloride

Trigonelline hydrochloride

Synonym(s):1-Methylpyridinium-3-carboxylate hydrochloride;N-Methylnicotinic acid betaine hydrochloride;Trigonelline hydrochloride

  • CAS NO.:6138-41-6
  • Empirical Formula: C7H8ClNO2
  • Molecular Weight: 173.6
  • MDL number: MFCD00077250
  • EINECS: 228-119-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2025-01-27 09:38:02
Trigonelline hydrochloride Structural

What is Trigonelline hydrochloride?

Description

Trigonelline hydrochloride (N-methylnicotinic acid betaine hydrochloride) is a betaine type pyrimidine alkaloid found in various seeds, including coffee beans. Trigonelline is synthesized from nicotinic acid in many plant species. It has been reported that trigonelline has diverse biological activities, such as hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities. (The product is for research purpose only.)

The Uses of Trigonelline hydrochloride

Trigonelline (chloride) is an alkaloid found in plants and coffee. Trigonelline is a product of niacin metabolism that is excreted in urine.

What are the applications of Application

Trigonelline hydrochloride is an analytical standard for proteomics research

References

Trigonelline: a plant alkaloid with therapeutic potential for diabetes and central nervous system disease (a review)
J. Zhou, L. Chan, S. Zhou, Curr. Med. Chem. 2012, 19, 3523.
A Review on Biosynthesis, Analytical Techniques, and Pharmacological Activities of Trigonelline as a Plant Alkaloid
N. Mohamadi, F. Sharififar, M. Pournamdari, M. Ansari, J. Dietary Suppl. 2018, 15, 207.

Properties of Trigonelline hydrochloride

Melting point: ~260 °C (dec.)
storage temp.  Inert atmosphere,Room Temperature
solubility  Methanol (Slightly), Water
form  neat
form  Solid
color  White to Off-White
Merck  14,9694
BRN  3734169
Stability: Hygroscopic
CAS DataBase Reference 6138-41-6(CAS DataBase Reference)

Safety information for Trigonelline hydrochloride

Computed Descriptors for Trigonelline hydrochloride

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