L-Lysine hydrochloride

Chemical properties

L-Lysine hydrochloride is a white crystalline powder; soluble in water (91.3 mg/ml at 20° C). insoluble in ethanol, acetone, ethyl ether, and benzene. It melts at about 260°C with decomposition. Store at room temperature.

The Uses of L-Lysine hydrochloride

L-Lysine monohydrochloride is widely used as nutritional supplements in food and beverage industries. It can also be used in animal feed as source of L-Lysine.? L-Lysine Monohydrochloride can be used in a wide variety of industries including: food production, beverage, pharmaceutical, agriculture/animal feed, and various other industries.

Definition

ChEBI: L-lysine hydrochloride is the hydrochloride salt of L-lysine It contains a L-lysine.

Biochem/physiol Actions

L-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. L-lysine lowers the cholesterol level by producing carnitine. L-lysine aids in calcium, zinc and iron absorption. Athletes take L-lysine as a supplement for lean mass building and for proper muscle and bone health. L-lysine competes with arginine during viral replication and reduces herpes simplex virus infection. L-lysine supplementation reduces chronic anxiety in human. Lysine reduces viscosity of serum albumin solution for injections.

Benefits

L-Lysine hydrochloride benefits the human body as a source of supplemental lysine, which helps relieve anxiety, prevents bone loss and osteoporosis, promotes healthy skin growth, treats shingles, regulates blood pressure, and prevents arterial plaque build-up, among other effects. In addition, L-Lysine hydrochloride added to feed as a supplement has shown significant effects on broiler weight gain, feed consumption and feed efficiency.

Safety Profile

iWdly toxic by ingestion. When heated to decomposition it emits very toxic fumes of HCl and NOx.

Purification Methods

Likely impurities are arginine, D-lysine, 2,6-diaminoheptanedioic acid and glutamic acid. Crystallise the monohydrochloride from water at pH 4-6 by adding 4 volumes of EtOH. At above 60% relative humidity it forms a dihydrate. [Birhbaum et al. J Biol Chem 194 455, 468 1952, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.]