Sodium chlorite

The Uses of Sodium chlorite

Sodium chlorite is used in the in situ generation of chlorine dioxide for stripping of textiles, bleaching, pulp and paper industries. It acts as a disinfectant in water treatment plant and as a preservative in eye drops. It is also used in contact lens cleaning solution and for sanitizing air ducts. It is associated with zinc chloride and used as a component in therapeutic rinses, toothpastes, mouth sprays and gels. It is utilized for the synthesis of 4-oxo-2-alkenoic acids from alkyl furans. Further, it is involved as a reagent in Pinnick oxidation reaction to prepare carboxylic acid from aldehydes.

The Uses of Sodium chlorite

A fresh solution of sodium phosphate buffer (40 mL, pH ~6.5) consisting of a 1:1 solution of NaH2PO4 (20 mL, 0.67 M) and Na2HPO4 (20 mL, 0.67 M) was prepared. A mixture of the SM (2.1 g, 8.64 mmol), TEMPO (0.094 g, 0.604 mmol), and sodium phosphate buffer (32.2 mL, 21.59 mmol, 0.67 M) in ACN (30 mL) heated to 35 C. Solutions of NaClO2 (3.91 g, 34.5 mmol) in H2O (4.5 mL) and bleach (4.3 mL, 6% wt) were added simultaneously over 40 min. The reaction was monitored by HPLC. After 2 h, ~30% SM remained. After 6 h, ~10% SM remained. Additional bleach (100 uL) was added, and the reaction was left at RT overnight. Additional bleach (100 uL) was added. The resulting mixture was stirred at 35 C for 2 h, after which time HPLC indicated a complete conversion. The reaction mixture was quenched by the slow addition of solution of Na2SO3 (2.07 mL, 43.2 mmol) in H2O (90 mL) at 0 C, resulting in the disappearance of the brown reaction color. The solvent was removed in vacuo, and the remaining aq residue was extracted with EtOAc (3 x 40 mL). The organics were combined, washed with H2O (8 mL), brine (8 mL), dried (Na2SO4), and concentrated to provide the product as a pale yellow solid. [2.2 g, 99%]

What are the applications of Application

Sodium chlorite is an oxidative reagent