Sodium acetate
Synonym(s):Acetic acid sodium salt;Sodium acetate;Sodium acetate buffer 3M;Sodium Acetate, Anhydrous, Molecular Biology Grade - CAS 127-09-3 - Calbiochem
- CAS NO.:127-09-3
- Empirical Formula: C2H3NaO2
- Molecular Weight: 82.03379
- MDL number: MFCD00012459
- EINECS: 204-823-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-16 10:38:43
What is Sodium acetate?
Absorption
It is readily available in the circulation after IV administration.
Toxicity
LD50: 25956 mg/kg (Rat.)
Description
Sodium acetate (CH3COONa) is the sodium salt of acetic acid. It appears as a colorless deliquescent salt with a wide range of applications. In industry, it can be used in textile industry to neutralize sulfuric acid waste streams and as a photoresist upon using aniline dyes. In concrete industry, it can be used as a concrete sealant to mitigate the water damage. In food, it can be used as a seasoning. It can also be used as a buffer solution in lab. In addition, it is also used in heating pads, hand warmers and hot ice. For laboratory use, it can be produced by the reaction between acetate with the sodium carbonate, sodium bicarbonate and sodium hydroxide. In industry, it is prepared from the glacial acetic acid and sodium hydroxide.
Description
Sodium acetate (NaOAc) is the sodium salt of acetic acid. It is generally used in organic chemistry as a weak base. Potassium acetate (KOAc) is used more commonly than sodium acetate, usually as a base in palladium catalyzed reactions.
The Uses of Sodium acetate
Used as buffers.
Acidity regulation (buffering)
Sodium acetate mixed with acetic acid forms a pH buffer, which can be used to stabilise the pH of foods in the pH-range from 3 to 6. The table below gives indicative values of the composition needed to give a certain pH. The mixtures below can be diluted at least 10 times with minimum effect on pH, however, the stability decreases.
The Uses of Sodium acetate
To a solution of the SM (80 g, 0.27 mol) in CHCl3 (1 L) at 10-15 C was added dropwise a solution of Br2 (16 mL, 0.31 mol) in CHCl3 (100 mL). The reaction was stirred at 12 C for 10 min, then washed sequentially with cooled sat aq NaHCO3 (2 x 500 mL) and sat aq brine (400 mL), dried, and concentrated in vacuo. Crystallization of the residue from EtOAc provided the product as a yellow solid. [90 g, 88%]
What are the applications of Application
Sodium Acetate, Anhydrous is for precipitation of nucleic acids and preparation of gel stains for protein gel electrophoresis
What are the applications of Application
Sodium acetate buffer solution is 3 M, non-sterile; 0.2 μm filtered, may be used in a variety of molecular biology applications. pH 5.2±0.1
Background
Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct sodium levels in hyponatremic patients. It can be used also in metabolic acidosis and for urine alkalinization.
Indications
Injection, USP 40 mEq is indicated as a source of sodium, for addition to large volume intravenous fluids to prevent or correct hyponatremia in patients with restricted or no oral intake. It is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions. Sodium acetate and other bicarbonate precursors are alkalinising agents, and can be used to correct metabolic acidosis, or for alkalinisation of the urine.
Pharmacokinetics
Sodium is the principal cation of extracellular fluid. It comprises more than 90% of total cations at its normal plasma concentration of approximately 140 mEq/liter. The sodium ion exerts a primary role in controlling total body water and its distribution. Acetate ions acts as hydrogen ion acceptor which is alternative to bicarbonate.
Metabolism
In liver, sodium acetate is being metabolized into bicarbonate. To form bicarbonate, acetate is slowly hydrolyzed to carbon dioxide and water, which are then converted to bicarbonate by the addition of a hydrogen ion.
Properties of Sodium acetate
Melting point: | >300 °C (dec.)(lit.) |
Density | 1.01 g/mL at 20 °C |
Flash point: | >250 °C |
storage temp. | Store at +5°C to +30°C. |
solubility | H2O: 3 M at 20 °C, clear, colorless |
form | powder |
appearance | White powder |
color | white |
Odor | Slight acetic acid |
Water Solubility | 500 g/L (20 ºC) |
Sensitive | Hygroscopic |
Boiling point: | >400°C(decomposition) |
Safety information for Sodium acetate
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H320:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Sodium acetate
InChIKey | VMHLLURERBWHNL-UHFFFAOYSA-M |
Abamectin manufacturer
SAGAR LIFE SCIENCES PVT LTD
Mahadev Pharmaceuticals
Rishi Chemical Works Pvt Ltd
JAY FINECHEM PVT LTD
ALLIPO CHEMICALS
Cefa-Cilinas Biotics Pvt Ltd
JSK Chemicals
New Products
3-N-BOC-(S)-AMINO BUTYRONITRILE 4-Piperidinopiperidine 2-Methyl-4-nitrobenzoic acid 2-(4-bromophenyl)-2-methylpropanoic acid 4-Acetyl-2-methylbenzoicacid Acetyl-meldrum's acid Ethyl-4-Pyrazole carboxylate 2,6 Di acetylpyridine 2,6-Pyridinedimethanol 5,7-Dichloro-3H-Imidazo[4,5-B]Pyridine 5-Bromo-2-Methoxy-4-Methyl-3-Nitropyridine 2-Fluoro-5-Iodopyridine 2-Fluoro-5-Methylpyridine 2-Chloro-3-Bromo-5-Amiopyridine METHYL-4-(BUTYRYLAMINO)3-METHYL-5-NITROBENZOATE TRANS-CYCLOBUTANE-1,2- DICARBOXYLIC ACID 5-Nitro indazole R-(-)-5-(2-AMINO-PROPYL)-2-METHOXY-BENZENESULFONAMIDE 1,3-cyclohexanedione 4-Aminophenaethylalchol 3-NITRO-5-ACETYL IMINODIBENZYL (S)-(+)-4-BENZYL-2-OXAZOLIDINONE 4-FLUORO PHENYL MAGNESIUM BROMIDE 1.0 M IN THF 1-HYDROXY-4-METHYL6-(2,4,4-TRI METHYL PHENYL)-2-PYRIDONE MONO ETHANOL AMINE(PIROCTONE OLAMINE)Related products of tetrahydrofuran
You may like
-
127-09-03 SODIUM ACETATE ANHYDROUS 99%View Details
127-09-03 -
SODIUM ACETATE 99%View Details
-
Sodium acetate, anhydrous, 98% 99%View Details
-
Sodium Acetate 99%View Details
-
Sodium Acetate Anhydrous 99%View Details
-
Sodium acetate anhydrous 99%View Details
-
Sodium acetate 99%View Details
-
Sodium acetate 98%View Details