Sodium bicarbonate

Description

Sodium bicarbonate, which is the compound commonly called baking soda, exists as a white, odorless, crystalline solid. It occurs naturally as the mineral nahcolite, which derives its name from its chemical formula by replacing the “3” in NaHCO₃ with the ending “lite.” The world’s main source of nahcolite is the Piceance Creek Basin in western Colorado, which is part of the larger Green River formation. Sodium bicarbonate is extracted using solution mining by pumping hot water through injection wells to dissolve the nahcolite from the Eocene beds where it occurs 1,500 to 2,000 feet below the surface. The dissolved sodium bicarbonate is pumped to the surface where it is treated to recover NaHCO₃ from solution. Sodium bicarbonate can also be produced from the trona deposits, which is a source of sodium carbonates (see Sodium Carbonate).

Description

Sodium bicarbonate (NaHCO3) is commonly referred to as baking soda by people outside of chemistry. It is amphoteric, meaning it can neutralize both acids and bases. The most common use of NaHCO3 is as a saturated aqueous solution for performing a basic wash during an aqueous workup.

Description

Sodium hydrogen carbonate (sodium bicarbonate, NaHCO3) is a time-honored remedy for acid indigestion. It gives off CO2 when it is heated, which makes cakes and cookies rise during baking. It can also remove ink buildup from printing presses, and it is an environmentally friendly alternative to sandblasting for removing graffiti from buildings.

The Uses of Sodium bicarbonate

sodium bicarbonate (baking soda) is an inorganic salt used as a buffering agent and a pH adjuster, it also serves as a neutralizer. It is used in skin-smoothing powders.

The Uses of Sodium bicarbonate

DPPA (642 mg, 2.34 mmol) and TEA (236 mg, 2.34 mmol) were added to a solution of the SM (300 mg, 2.34 mmol) in t-BuOH (10 mL) at 50 C. The reaction mixture was stirred at 90 C for 16 h. After concentration, the residue was purified by silica gel column chromatography (1:4 PE/EtOAc) to provide the product as a yellow solid. [412 mg, 66%]

What are the applications of Application

Sodium bicarbonate is a commonly used laboratory pH neutralizer that reacts with acids and bases

Indications

Sodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Also is indicated in severe diarrhea which is often accompanied by a significant loss of bicarbonate. Further indicated in the treatment of certain drug intoxications, including barbiturates (where dissociation of the barbiturateprotein complex is desired), in poisoning by salicylates or methyl alcohol and in hemolytic reactions requiring alkalinization of the urine to diminish nephrotoxicity of blood pigments.

Background

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

Pharmacokinetics

Intravenous sodium bicarbonate therapy increases plasma bicarbonate, buffers excess hydrogen ion concentration, raises blood pH and reverses the clinical manifestations of acidosis.

Metabolism

Not Available