N-Methylmaleimide
- CAS NO.：930-88-1
- Empirical Formula: C5H5NO2
- Molecular Weight: 111.1
- MDL number: MFCD00005508
- EINECS: 213-226-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-24 19:19:26
What is N-Methylmaleimide?
Chemical properties
light yellow crystals
The Uses of N-Methylmaleimide
N-Methylmaleimide is an electron deficient olefin that acts as a thiol-blocking reagent.
What are the applications of Application
N-Methylmaleimide is a thiol-blocking reagent
Synthesis Reference(s)
The Journal of Organic Chemistry, 60, p. 6676, 1995 DOI: 10.1021/jo00126a013
Purification Methods
Crystallise the imide three times from diethyl ether. Dry it in vacuo.[Beilstein 21/10 V 5.]
Properties of N-Methylmaleimide
| Melting point: | 94-96 °C (lit.) |
| Boiling point: | 208.19°C (rough estimate) |
| Density | 1.3113 (rough estimate) |
| refractive index | 1.4260 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| pka | -2.18±0.20(Predicted) |
| form | Crystals |
| color | Light yellow |
| Water Solubility | Slightly soluble in water. |
| BRN | 108550 |
| CAS DataBase Reference | 930-88-1(CAS DataBase Reference) |
| NIST Chemistry Reference | N-Methylmaleimide(930-88-1) |
Safety information for N-Methylmaleimide
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-Methylmaleimide
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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