Hydrocortisone 21-hemisuccinate
Synonym(s):11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate;11β,17aα,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate;Cortisol 21-hemisuccinate;Hydrocortisone 21-hemisuccinate;Hydrocortisone 21-hemisuccinate monohydrate
- CAS NO.：2203-97-6
- Empirical Formula: C25H34O8
- Molecular Weight: 462.53
- MDL number: MFCD00046256
- EINECS: 218-612-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-25 11:31:46
What is Hydrocortisone 21-hemisuccinate?
Chemical properties
White or almost white, hygroscopic powder
The Uses of Hydrocortisone 21-hemisuccinate
Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.
The Uses of Hydrocortisone 21-hemisuccinate
glucocorticoid
What are the applications of Application
Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent
Definition
ChEBI: A derivative of succinic acid in which one of the carboxy groups is esterified by the C-21 hydroxy group of cortisol (hydrocortisone).
brand name
A-Hydrocort (Abbott); A-Hydrocort (Hospira); Solu-Cortef (Pharmacia & Upjohn).
Metabolism
Not Available
Properties of Hydrocortisone 21-hemisuccinate
| Melting point: | 170～172℃ |
| Boiling point: | 685.5±55.0 °C(Predicted) |
| alpha | [α]D20 +147～+153° (c=1, C2H5OH) (After Drying) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | Practically insoluble in water, freely soluble in acetone and in anhydrous ethanol. It dissolves in dilute solutions of alkali carbonates and alkali hydroxides. |
| form | neat |
| form | Solid |
| pka | pKa 5.10/5.64(20% aq EtOH/50% aq EtOH) (Uncertain) |
| color | White to Off-White |
Safety information for Hydrocortisone 21-hemisuccinate
| Signal word | Danger |
| Pictogram(s) |
 Health Hazard GHS08 |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for Hydrocortisone 21-hemisuccinate
Hydrocortisone 21-hemisuccinate manufacturer
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