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HomeProduct name listHydrocortisone 21-hemisuccinate

Hydrocortisone 21-hemisuccinate

Synonym(s):11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate;11β,17aα,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate;Cortisol 21-hemisuccinate;Hydrocortisone 21-hemisuccinate;Hydrocortisone 21-hemisuccinate monohydrate

  • CAS NO.:2203-97-6
  • Empirical Formula: C25H34O8
  • Molecular Weight: 462.53
  • MDL number: MFCD00046256
  • EINECS: 218-612-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-01 18:09:03
Hydrocortisone 21-hemisuccinate Structural

What is Hydrocortisone 21-hemisuccinate?

Chemical properties

White or almost white, hygroscopic powder

The Uses of Hydrocortisone 21-hemisuccinate

Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.

The Uses of Hydrocortisone 21-hemisuccinate

glucocorticoid

What are the applications of Application

Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent

Definition

ChEBI: A derivative of succinic acid in which one of the carboxy groups is esterified by the C-21 hydroxy group of cortisol (hydrocortisone).

brand name

A-Hydrocort (Abbott); A-Hydrocort (Hospira); Solu-Cortef (Pharmacia & Upjohn).

Metabolism

Not Available

Properties of Hydrocortisone 21-hemisuccinate

Melting point: 170~172℃
Boiling point: 685.5±55.0 °C(Predicted)
alpha  [α]D20 +147~+153° (c=1, C2H5OH) (After Drying)
Density  1.33±0.1 g/cm3(Predicted)
storage temp.  −20°C
solubility  Practically insoluble in water, freely soluble in acetone and in anhydrous ethanol. It dissolves in dilute solutions of alkali carbonates and alkali hydroxides.
form  neat
form  Solid
pka pKa 5.10/5.64(20% aq EtOH/50% aq EtOH) (Uncertain)
color  White to Off-White

Safety information for Hydrocortisone 21-hemisuccinate

Signal word Danger
Pictogram(s)
ghs
Health Hazard
GHS08
Precautionary Statement Codes P201:Obtain special instructions before use.
P202:Do not handle until all safety precautions have been read and understood.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313:IF exposed or concerned: Get medical advice/attention.
P405:Store locked up.
P501:Dispose of contents/container to..…

Computed Descriptors for Hydrocortisone 21-hemisuccinate

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