2203-97-6
Product Name:
Hydrocortisone 21-hemisuccinate
Formula:
C25H34O8
Synonyms:
11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate;11β,17aα,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate;Cortisol 21-hemisuccinate;Hydrocortisone 21-hemisuccinate;Hydrocortisone 21-hemisuccinate monohydrate
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Collision Cross Section | 212.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
|---|
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Health Hazard GHS08 |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..… |
COMPUTED DESCRIPTORS
| Molecular Weight | 462.5 g/mol |
|---|---|
| XLogP3 | 1.8 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 7 |
| Exact Mass | 462.22536804 g/mol |
| Monoisotopic Mass | 462.22536804 g/mol |
| Topological Polar Surface Area | 138 Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 908 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 7 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Hydrocortisone succinate is a derivative of succinic acid in which one of the carboxy groups is esterified by the C-21 hydroxy group of cortisol (hydrocortisone). It is a dicarboxylic acid monoester, a hemisuccinate and a tertiary alpha-hydroxy ketone. It is functionally related to a cortisol.