CORTEXOLONE
Synonym(s):Cortexolone;11-Deoxycortisol;17α,21-Dihydroxy-4-pregnene-3,20-dione;17α-Hydroxycortexone;17,21-Dihydroxy-4-pregnene-3,20-dione
- CAS NO.：152-58-9
- Empirical Formula: C21H30O4
- Molecular Weight: 346.46
- MDL number: MFCD00003662
- EINECS: 205-805-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-30 14:17:11
What is CORTEXOLONE?
Chemical properties
Crystalline Solid
The Uses of CORTEXOLONE
Glucocorticoid receptor binding
The Uses of CORTEXOLONE
11-Deoxy Cortisol (Hydrocortisone EP Impurity F) is a glucocorticoid receptor binding.
What are the applications of Application
11-Deoxy Cortisol is aids in glucocorticoid receptor binding.
Definition
ChEBI: 11-deoxycortisol is a deoxycortisol that is cortisol in which the hydroxy group at position 11 has been replaced by a hydrogen. It has a role as a mouse metabolite and a human metabolite. It is a glucocorticoid, a primary alpha-hydroxy ketone, a tertiary alpha-hydroxy ketone and a deoxycortisol.
Properties of CORTEXOLONE
| Melting point: | 205-208 °C |
| Boiling point: | 401.19°C (rough estimate) |
| Density | 1.22±0.1 g/cm3 (20 ºC 760 Torr) |
| refractive index | 120 ° (C=1, Dioxane) |
| Flash point: | 9℃ |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Dioxane (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly, Heat |
| form | Solid |
| pka | 12?+-.0.60(Predicted) |
| color | White to Off-White |
| Water Solubility | 44.08mg/L(37 ºC) |
| Merck | 14,2932 |
| CAS DataBase Reference | 152-58-9(CAS DataBase Reference) |
Safety information for CORTEXOLONE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H370:Specific target organ toxicity, single exposure |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for CORTEXOLONE
| InChIKey | WHBHBVVOGNECLV-OBQKJFGGSA-N |
Abamectin manufacturer
Bulat Pharmaceutical Pvt Ltd
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product: 152-58-9 Cortexolone Clascoterone Intermediate 98%
Allmpus Laboratories Pvt Ltd
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Phone:+9109518738415
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product: Hydrocortisone EP Impurity F 152-58-9 97.94
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