Homophthalic acid

Synonym(s):α-Carboxy-o-toluic acid;2-Carboxyphenylacetic acid

CAS NO.：89-51-0
Empirical Formula: C9H8O4
Molecular Weight: 180.16
MDL number: MFCD00004326
EINECS: 201-913-9
SAFETY DATA SHEET (SDS)
Update Date: 2023-12-22 17:53:22

What is Homophthalic acid?

Chemical properties

off-white to light yellow or pale green powder

The Uses of Homophthalic acid

antidepressant

The Uses of Homophthalic acid

A remainder phthalic acid.

What are the applications of Application

Homophthalic acid is a remainder phthalic acid

Synthesis Reference(s)

The Journal of Organic Chemistry, 58, p. 4745, 1993 DOI: 10.1021/jo00069a047

Purification Methods

Crystallise the acid from boiling H2O (25mL/g; 63mL/g at 20o), aqueous AcOH (m 180o) Dry it at 100o. The S-benzylisothiuronium salt has m 155-156o (from EtOH). [Price Org Synth 22 611942, Grummitt et al. Org Synth Coll Vol III 449 1955, Beilstein 9 H 857, 9 II 617, 9 III 4266, 9 IV 3343.] The anhydride [703-59-3] M 162.1 has m 141-142o. [Beilstein 17/11 V 270.]

Properties of Homophthalic acid

Melting point:	178-182 °C (lit.)
Boiling point:	389.5±17.0 °C(Predicted)
Density	1.392±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	soluble in Dimethylformamide
form	Powder
pka	3.72±0.36(Predicted)
color	Off-white to light yellow or pale green
Water Solubility	12 g/L (20 ºC)
BRN	1872069
CAS DataBase Reference	89-51-0(CAS DataBase Reference)
EPA Substance Registry System	Benzeneacetic acid, 2-carboxy- (89-51-0)

Safety information for Homophthalic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.