Dimedone
Synonym(s):Dimedone;Methone
- CAS NO.:126-81-8
- Empirical Formula: C8H12O2
- Molecular Weight: 140.18
- MDL number: MFCD00001588
- EINECS: 204-804-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-30 18:52:02
What is Dimedone?
Chemical properties
solid
The Uses of Dimedone
Reagent used in synthesis of fused 3-methylfuransDimedone is used in organic chemistry to identify the presence of aldehyde group. It is also used as a catalyst in the formation of transition-metal complexes. Further, it is also employed in colorimetry, crystallography, luminescence and spectrophotometric analysis. In addition to this, it is used in the synthesis of naturally occurring fused 3-methylfurans.
The Uses of Dimedone
Part of furannulation strategy for the synthesis of naturally occurring fused 3-methylfurans.1
The Uses of Dimedone
A mentha compound showing antimicrobial properties against common bacteria in the food industry such as E.coli and P.aeruginosa as well as strains of yeast.
The Uses of Dimedone
Used in the synthesis of fused 3-methylfurans via furannulation.
Synthesis Reference(s)
Journal of the American Chemical Society, 77, p. 6656, 1955 DOI: 10.1021/ja01629a086
Organic Syntheses, Coll. Vol. 2, p. 200, 1943
General Description
5,5-dimethyl-1,3-cyclohexanedione (Dimedone) is basically a highly sensitive and very specific reagent used for the determination of aldehydes. It is highly advantageous as it is environment friendly, give high yields and is a simple workup procedure.
Purification Methods
Crystallise dimedone from acetone (ca 8mL/g), water or aqueous EtOH. Dry it in air. [Schneider & Todd Org Synth Coll Vol II 200 1943, Beilstein 7 H 559, 7 IV 1999.]
Properties of Dimedone
Melting point: | 146-148 °C (lit.) |
Boiling point: | 216.69°C (rough estimate) |
Density | 1.0373 (rough estimate) |
refractive index | 1.4787 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | 4.01g/l |
form | Liquid |
pka | 4.8(at 25℃) |
color | Clear colorless to yellow |
Water Solubility | 0.416 g/100 mL (25 ºC) |
Merck | 14,3242 |
BRN | 471489 |
Stability: | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 126-81-8(CAS DataBase Reference) |
NIST Chemistry Reference | Dimedone(126-81-8) |
EPA Substance Registry System | 1,3-Cyclohexanedione, 5,5-dimethyl- (126-81-8) |
Safety information for Dimedone
Signal word | Warning |
Pictogram(s) |
Flame Flammables GHS02 Health Hazard GHS08 |
GHS Hazard Statements |
H228:Flammable solids H317:Sensitisation, Skin H334:Sensitisation, respiratory H350:Carcinogenicity H360:Reproductive toxicity H373:Specific target organ toxicity, repeated exposure |
Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P285:In case of inadequate ventilation wear respiratory protection. P363:Wash contaminated clothing before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P341:IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. P308+P313:IF exposed or concerned: Get medical advice/attention. P342+P311:IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. P403:Store in a well-ventilated place. |
Computed Descriptors for Dimedone
InChIKey | BADXJIPKFRBFOT-UHFFFAOYSA-N |
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