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HomeProduct name listDimedone

Dimedone

Synonym(s):Dimedone;Methone

  • CAS NO.:126-81-8
  • Empirical Formula: C8H12O2
  • Molecular Weight: 140.18
  • MDL number: MFCD00001588
  • EINECS: 204-804-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:52
Dimedone Structural

What is Dimedone?

Chemical properties

solid

The Uses of Dimedone

Reagent used in synthesis of fused 3-methylfuransDimedone is used in organic chemistry to identify the presence of aldehyde group. It is also used as a catalyst in the formation of transition-metal complexes. Further, it is also employed in colorimetry, crystallography, luminescence and spectrophotometric analysis. In addition to this, it is used in the synthesis of naturally occurring fused 3-methylfurans.

The Uses of Dimedone

Part of furannulation strategy for the synthesis of naturally occurring fused 3-methylfurans.1

The Uses of Dimedone

A mentha compound showing antimicrobial properties against common bacteria in the food industry such as E.coli and P.aeruginosa as well as strains of yeast.

The Uses of Dimedone

Used in the synthesis of fused 3-methylfurans via furannulation.

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 6656, 1955 DOI: 10.1021/ja01629a086
Organic Syntheses, Coll. Vol. 2, p. 200, 1943

General Description

5,5-dimethyl-1,3-cyclohexanedione (Dimedone) is basically a highly sensitive and very specific reagent used for the determination of aldehydes. It is highly advantageous as it is environment friendly, give high yields and is a simple workup procedure.

Purification Methods

Crystallise dimedone from acetone (ca 8mL/g), water or aqueous EtOH. Dry it in air. [Schneider & Todd Org Synth Coll Vol II 200 1943, Beilstein 7 H 559, 7 IV 1999.]

Properties of Dimedone

Melting point: 146-148 °C (lit.)
Boiling point: 216.69°C (rough estimate)
Density  1.0373 (rough estimate)
refractive index  1.4787 (estimate)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  4.01g/l
form  Liquid
pka 4.8(at 25℃)
color  Clear colorless to yellow
Water Solubility  0.416 g/100 mL (25 ºC)
Merck  14,3242
BRN  471489
Stability: Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference 126-81-8(CAS DataBase Reference)
NIST Chemistry Reference Dimedone(126-81-8)
EPA Substance Registry System 1,3-Cyclohexanedione, 5,5-dimethyl- (126-81-8)

Safety information for Dimedone

Signal word Warning
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Health Hazard
GHS08
GHS Hazard Statements H228:Flammable solids
H317:Sensitisation, Skin
H334:Sensitisation, respiratory
H350:Carcinogenicity
H360:Reproductive toxicity
H373:Specific target organ toxicity, repeated exposure
Precautionary Statement Codes P201:Obtain special instructions before use.
P202:Do not handle until all safety precautions have been read and understood.
P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P272:Contaminated work clothing should not be allowed out of the workplace.
P285:In case of inadequate ventilation wear respiratory protection.
P363:Wash contaminated clothing before reuse.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P304+P341:IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P308+P313:IF exposed or concerned: Get medical advice/attention.
P342+P311:IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P403:Store in a well-ventilated place.

Computed Descriptors for Dimedone

InChIKey BADXJIPKFRBFOT-UHFFFAOYSA-N

Dimedone manufacturer

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