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HomeProduct name listD-(+)-Norephedrine

D-(+)-Norephedrine

Synonym(s):(1S,2R)-2-Amino-1-phenyl-1-propanol;erythro-α-(1-aminoethyl)benzyl alcohol;D-(+)-Norephedrine;Phenylpropanolamine

  • CAS NO.:37577-28-9
  • Empirical Formula: C9H13NO
  • Molecular Weight: 151.21
  • MDL number: MFCD00064411
  • EINECS: 628-077-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-15 10:43:31
D-(+)-Norephedrine Structural

What is D-(+)-Norephedrine?

The Uses of D-(+)-Norephedrine

(1S,2R)-(+)-Norephedrine Hydrochloride is used in preparation of pyrrolopyridines as ERK inhibitors useful in treatment of diseases.

Definition

ChEBI: (+)-norephedrine is an amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1S,2R-stereoisomer). It is a member of amphetamines and a phenethylamine alkaloid.

Properties of D-(+)-Norephedrine

Melting point: 51-54 °C(lit.)
Boiling point: 288.1±20.0 °C(Predicted)
alpha  40 º (c=7, 1M HCl)
Density  1.071±0.06 g/cm3(Predicted)
Flash point: >230 °F
storage temp.  2-8°C
pka 12.07±0.45(Predicted)
optical activity [α]20/D +40°, c = 7 in 1 M HCl
BRN  2802896
CAS DataBase Reference 37577-28-9(CAS DataBase Reference)
NIST Chemistry Reference (1S,2r)-(+)-norephedrine(37577-28-9)

Safety information for D-(+)-Norephedrine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for D-(+)-Norephedrine

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