Asiatic acid

Synonym(s):2α,23-Dihydroxyursolic acid;Dammarolic acid;NSC 166063

CAS NO.：464-92-6
Empirical Formula: C30H48O5
Molecular Weight: 488.7
MDL number: MFCD00238541
EINECS: 482-720-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-05 08:26:49

What is Asiatic acid?

The Uses of Asiatic acid

Asiatic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Asiatic Acid is a neuroprotectant and induces of apoptosis in HepG2 human hepatoma cells.

The Uses of Asiatic acid

wound healing, experimental carcinogen

The Uses of Asiatic acid

Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. It is a starting material for asiatic acid derivative synthesis for use as anticancer agents, glycogen phosphorylase inhibitors and and hepatoprotectants.

What are the applications of Application

Asiatic acid is a pentacyclic triterpene that is known to stimulate wound healing by increasing collagen production

Definition

ChEBI: A pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta stereoisomer). It is isolated from Symplocos lancifolia and Vateria indica and exhibits anti-angiogenic activity.

General Description

Asiatic acid is a naturally occurring pentacyclic triterpenoid, obtained from Centella asiatica.

Biochem/physiol Actions

Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties.

Properties of Asiatic acid

Melting point:	325-330 °C(lit.)
Boiling point:	609.4±55.0 °C(Predicted)
Density	1.18±0.1 g/cm3(Predicted)
RTECS	YU9580000
storage temp.	2-8°C
solubility	methanol: soluble1mg/mL, clear, colorless
form	powder
pka	4.66±0.70(Predicted)
color	white
Water Solubility	Soluble in dimethyl sulfoxide, ethanol and dimethylformamide. Sparingly soluble in water
CAS DataBase Reference	464-92-6(CAS DataBase Reference)

Safety information for Asiatic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H413:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment.