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HomeProduct name list(3R)-(-)-3-Aminopyrrolidine dihydrochloride

(3R)-(-)-3-Aminopyrrolidine dihydrochloride

  • CAS NO.:116183-81-4
  • Empirical Formula: C4H12Cl2N2
  • Molecular Weight: 159.06
  • MDL number: MFCD00070604
  • EINECS: 634-214-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
(3R)-(-)-3-Aminopyrrolidine dihydrochloride Structural

What is (3R)-(-)-3-Aminopyrrolidine dihydrochloride?

Chemical properties

(R)-3-Aminopyrrolidine dihydrochloride is an optically active 3-aminopyrrolidine derivative, which can be used as a key intermediate in the synthesis of chiral drugs or pesticides.

The Uses of (3R)-(-)-3-Aminopyrrolidine dihydrochloride

(R)-3-Aminopyrrolidine dihydrochloride is a key intermediate in the synthesis of chiral drugs or pesticides, and it can be used in the synthesis of vinylpyrrolidone-Cephaloridine drugs.

Synthesis

(3R)-(-)-3-Aminopyrrolidine dihydrochloride was prepared by reacting (R)-3-(tert-butoxycarbonyl-amino)-pyrrolidine in methanol with chloroform Sulfone at room temperature for 6-9 hours.

Properties of (3R)-(-)-3-Aminopyrrolidine dihydrochloride

Melting point: 283°C (dec.)
refractive index  -1.1 ° (C=10, H2O)
storage temp.  Inert atmosphere,Room Temperature
form  Powder
color  White to off-white
optical activity [α]20/D 1.8°, c = 1 in H2O
Water Solubility  very faint turbidity
Sensitive  Hygroscopic
BRN  5852700
CAS DataBase Reference 116183-81-4(CAS DataBase Reference)

Safety information for (3R)-(-)-3-Aminopyrrolidine dihydrochloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for (3R)-(-)-3-Aminopyrrolidine dihydrochloride

InChIKey NJPNCMOUEXEGBL-RZFWHQLPSA-N

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