3,4,5-Trimethoxyaniline

CAS NO.：24313-88-0
Empirical Formula: C9H13NO3
Molecular Weight: 183.2
MDL number: MFCD00008393
EINECS: 246-154-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-04-25 13:42:50

What is 3,4,5-Trimethoxyaniline?

Chemical properties

3,4,5-Trimethoxyaniline is off-white to beige-brown, grey or pink powder

The Uses of 3,4,5-Trimethoxyaniline

3,4,5-Trimethoxyaniline is a tri-substituted aniline derivative with sympatholytic activity. It is used in the preparation of a novel class of anticancer agents.

What are the applications of Application

3,4,5-Trimethoxyaniline can be used:
(1) As experimental studies, infrared spectra and laser Raman spectra of 3,4,5-trimethoxyaniline were investigated^[1].
(2) Tropanilisation, detropanilisation and Schiff base formation in the reaction of 3,4,5-trimethoxyaniline with tropanilide ions as organic reaction reagents^[2].

What are the applications of Application

[1] BANDANA SHARMA; Shweta P; Munish Kumar Yadav. MOLECULAR STRUCTURE, EXPERIMENTAL AND THEORETICAL (HF, DFT) SPECTRAL ANALYSIS OF 3,4,5- TRIMETHOXYANILINE[J]. Rasayan Journal of Chemistry, 2023. DOI:10.31788/rjc.2023.1628371.
[2] J. TSUNETSUGU; S. E; M SATO. ChemInform Abstract: TROPENYLATION, DETROPENYLATION AND SCHIFF BASE FORMATION IN THE REACTION OF 3,4,5-TRIMETHOXYANILINE WITH TROPENYLIUM ION[J]. ChemInform, 1975. DOI:10.1002/chin.197545221.

Properties of 3,4,5-Trimethoxyaniline

Melting point:	110-113 °C (lit.)
Boiling point:	316.88°C (rough estimate)
Density	1.1967 (rough estimate)
refractive index	1.4760 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	Powder
pka	4.35±0.10(Predicted)
color	Off-white to beige-brown, gray, or pink
BRN	642919
CAS DataBase Reference	24313-88-0(CAS DataBase Reference)
EPA Substance Registry System	3,4,5-Trimethoxyaniline (24313-88-0)

Safety information for 3,4,5-Trimethoxyaniline

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water.