(2-Hydroxypropyl)-γ-cyclodextrin

CAS NO.：128446-34-4
Empirical Formula: C48H80-nO40.(C3H7O)n
Molecular Weight: 0
MDL number: MFCD00148890
EINECS: 207-166-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-21 22:41:43

What is (2-Hydroxypropyl)-γ-cyclodextrin?

Chemical properties

white powder

The Uses of (2-Hydroxypropyl)-γ-cyclodextrin

For R&D use

What are the applications of Application

(2-Hydroxypropyl)-γ-cyclodextrin is a gamma cyclodextrin that is a derivative of an 8-membered sugar ring molecule

General Description

(2-Hydroxypropyl)-γ-cyclodextrin belongs to the class of cyclodextrin derivatives, which exhibit a greater extent of solubility in water compared to their parent compounds. It is widely used in parenteral formulations and solid dosage forms to aid in the improvement of their stability, dissolution, bioavailability, etc.

Properties of (2-Hydroxypropyl)-γ-cyclodextrin

Melting point:	52-55 °C(lit.)
Boiling point:	97-98 °C3 mm Hg(lit.)
Flash point:	>230 °F
storage temp.	2-8°C
solubility	H2O: soluble450mg/mL
form	Solid powder
color	white
PH	6-9 (2% in H2O)
optical activity	[α]20/D +145°, c = 1 in H2O
CAS DataBase Reference	128446-34-4(CAS DataBase Reference)

Safety information for (2-Hydroxypropyl)-γ-cyclodextrin

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.