TRIMETHYL-BETA-CYCLODEXTRIN
Synonym(s):2,3,6-Tri-O-methyl-β-cyclodextrin;TM-β-CD;TM‐β‐CyD;TRIMEB;Trimethyl-β-cyclodextrin
- CAS NO.:55216-11-0
- Empirical Formula: C63H112O35
- Molecular Weight: 1429.54
- MDL number: MFCD00010728
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is TRIMETHYL-BETA-CYCLODEXTRIN?
The Uses of TRIMETHYL-BETA-CYCLODEXTRIN
Trimethyl-β-cyclodextrin (CAS# 55216-11-0) is β-cyclodextrin (C987830) derivative used to solubilize steroids in aqueous solution to increase their bioavailability.
The Uses of TRIMETHYL-BETA-CYCLODEXTRIN
Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin may be used:
- To investigate the crystal structure of its complexes with m-iodophenol, 4-biphenylacetic acid and (R)- and (S)-flurbiprofen by X-ray analysis.
- To study the candidature of its complex with vitamin A for potential application as a drug delivery system for ophthalmic applications by high sensitivity fluorescence spectrometry and high pressure liquid chromatography (HPLC).
- In the determination of analyte composition in commercial samples by HPLC coupled to mass spectrometry (MS).
What are the applications of Application
Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin is a compound for chiral resolutions
General Description
Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin is a β-cyclodextrin derivative that finds potential use in pharmaceutical, food and cosmetic applications. Its attractive features include: the non-polar cavity desirable for its use as a molecular host for a wide range of molecules and its affinity for organic compounds in solution as well as crystalline phases.
Properties of TRIMETHYL-BETA-CYCLODEXTRIN
Melting point: | 170-178 °C(lit.) |
refractive index | 160 ° (C=1, CHCl3) |
storage temp. | 2-8°C |
solubility | H2O: 50 mg/mL, slightly turbid, colorless |
form | Solid powder or crystals |
color | White to off-white |
optical activity | [α]25/D +157±4°, c = 1% in H2O |
BRN | 78748 |
Safety information for TRIMETHYL-BETA-CYCLODEXTRIN
Computed Descriptors for TRIMETHYL-BETA-CYCLODEXTRIN
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ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
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2,6-DI-O-METHYL-BETA-CYCLODEXTRIN
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TRIACETYL-BETA-CYCLODEXTRIN
Heptakis-(2,6-di-O-butyl-3-O-acetyl)-beta-Cyclodextrin
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