2,5-Dimethylfuran

CAS NO.：625-86-5
Empirical Formula: C6H8O
Molecular Weight: 96.13
MDL number: MFCD00003250
EINECS: 210-914-3
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-21 22:41:43

What is 2,5-Dimethylfuran?

Description

2,5-Dimethylfuran is a low-boiling, flammable liquid. It is synthesized from fructose or glucose and has been promoted as a sustainable biofuel. Recently,?it was identified as a marker for cigarette smoke?for the purpose of evaluating workplace safety.

Chemical properties

clear colorless to amber liquid

Chemical properties

Colorless liquid; spicy smoky aroma

Occurrence

Reported found in beef, chicken, cocoa, coffee, egg, malt, rice, and rum.

The Uses of 2,5-Dimethylfuran

2,5-Dimethylfuran is a major metabolite of hexane with singlet oxygen scavenging ability. It is used as biofuel, biomaker for smoking, pharmaceutical intermediate and in organic synthesis. It is also used to analyze samples for the derivatization of carbonyl-containing compounds to their oximes.

The Uses of 2,5-Dimethylfuran

It is an ideal marker for detecting cigarette smoke.

What are the applications of Application

2,5-Dimethylfuran is a metabolite of hexane with singlet oxygen scavenging ability

Definition

ChEBI: 2,5-dimethylfuran is a member of the class of furans that is furan in which the hydrogens at positions 2 and 5 are replaced by methyl groups. It has a role as a human urinary metabolite, an antifungal agent, a bacterial metabolite, a fumigant, a fuel, a plant metabolite and a Maillard reaction product.

Aroma threshold values

Medium strength odor, meaty type; recommend smelling in a 10.0% solution or less.

Taste threshold values

Chemical meaty gravy taste at 30 ppm in water.

Synthesis Reference(s)

The Journal of Organic Chemistry, 54, p. 3475, 1989 DOI: 10.1021/jo00275a039
Synthesis, p. 209, 1973

General Description

Clear yellow oily liquid. Aromatic caustic odor.

Air & Water Reactions

Highly flammable. 2,5-Dimethylfuran may be sensitive to exposure to air(not vigorous). Insoluble in water.

Reactivity Profile

2,5-Dimethylfuran can react vigorously with oxidizing materials. 2,5-Dimethylfuran is also incompatible with strong acids and strong bases.

Fire Hazard

2,5-Dimethylfuran is flammable.

Properties of 2,5-Dimethylfuran

Melting point:	-62 °C
Boiling point:	92-94 °C(lit.)
Density	0.905 g/mL at 20 °C
vapor density	3.31 (vs air)
refractive index	n20/D 1.441(lit.)
FEMA	4106 \| 2,5-DIMETHYLFURAN
Flash point:	29 °F
storage temp.	Flammables area
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form	Liquid
color	Clear colorless to amber
Specific Gravity	0.903
Odor	at 10.00 % in propylene glycol. chemical ethereal meaty gravy roast beef bacon
Water Solubility	Slightly miscible with water. Miscible with ethanol and fats.
JECFA Number	1488
BRN	106449
Stability:	Light Sensitive, Volatile
CAS DataBase Reference	625-86-5(CAS DataBase Reference)
NIST Chemistry Reference	Furan, 2,5-dimethyl-(625-86-5)
EPA Substance Registry System	2,5-Dimethylfuran (625-86-5)

Safety information for 2,5-Dimethylfuran

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H225:Flammable liquids H302:Acute toxicity,oral H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.