N,N-Dimethylformamide

Description

Dimethylformamide—strictly,?N,N-dimethylformamide—is a valuable solvent in organic chemical reactions because of its polarity and low evaporation rate. Its preparation from dimethylamine chloride and formic acid was first described by A. Verley in 1893. It is also a common solvent for spectroscopy and a component of paint strippers.

Description

Dimethylformamide (DMF) is a polar aprotic solvent with a high boiling point (153 C). DMF is also used as a reagent in some reactions. A closely related solvent is dimethylacetamide (DMA).

The Uses of N,N-Dimethylformamide

N,N-Dimethylformamide (DMF) is a clear liquid that has been widely used in industries as a solvent, an additive, or an intermediate because of its extensive miscibility with water and most common organic solvents. Dimethylformamide solutions are used toprocess polymer fibers, films, and surface coatings; to permit easy spinning of acrylic fibers; to produce wire enamels, and as a crystallization medium in the pharmaceutical industry.
DMF can also be used for formylation with alkyllithium or Grignard reagents. It is used as a reagent in Bouveault aldehyde synthesis and also in Vilsmeier-Haack reaction. It acts as a catalyst in the synthesis of acyl chlorides. It is used for separating and refining crude from olefin gas. DMF along with methylene chloride acts as a remover of varnish or lacquers. It is also used in the manufacture of adhesives, fibers and films.

What are the applications of Application

N,N-Dimethylformamide is a strongly polar organic solvent