2-Bromopyrimidine
- CAS NO.：4595-60-2
- Empirical Formula: C4H3BrN2
- Molecular Weight: 158.98
- MDL number: MFCD00014601
- EINECS: 224-993-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-12-25 19:53:00
What is 2-Bromopyrimidine?
Chemical properties
Off-white crystalline powder
The Uses of 2-Bromopyrimidine
2-Bromopyrimidine is used in the preparation of 2,7-bis(2-pyrimidyl)-9,9-dihexylfluorene by cross-coupling with 9,9-dihexylfluorene-2,7-diboronic acid. It undergoes microwave-assisted aminocarbonylation at C-2 with palladium and molybdenum hexacarbonyl.
Preparation
The recent synthesis of 2-bromopyrimidine by diazotization of 2-aminopyrimidine in hydrobromic acid has furnished a convenient starting material for other 2-substituted pyrimidines.
General Description
2-Bromopyrimidine undergoes microwave-assisited aminocarbonylation at C-2 with palladium and Mo(CO)6.
Properties of 2-Bromopyrimidine
| Melting point: | 55-57 °C (lit.) |
| Boiling point: | 62-64°C (1.5 mmHg) |
| Density | 1.6448 (rough estimate) |
| refractive index | 1.5260 (estimate) |
| Flash point: | 62-64°C/1.5mm |
| storage temp. | -20°C |
| solubility | DMSO (Sparingly), Methanol (Slightly) |
| pka | -1.59±0.13(Predicted) |
| form | Crystalline Powder |
| color | Off-white |
| Water Solubility | Miscible with water. |
| BRN | 605945 |
| CAS DataBase Reference | 4595-60-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Pyrimidine, 2-bromo-(4595-60-2) |
| EPA Substance Registry System | Pyrimidine, 2-bromo- (4595-60-2) |
Safety information for 2-Bromopyrimidine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Bromopyrimidine
Abamectin manufacturer
SYNGREEN LIFESCIENCES PVT.LTD
2Y
Phone:+91-9849474297
Whatsapp: +91- 9849474297
product: 4595-60-2 2-Bromopyrimidine 98%
TANUJ PYRIDINE
1Y
Phone:+91-8790371027
Whatsapp: +91 8790371027
product: 4595-60-2 2-Bromopyrimidine 98%
JIVICHEM SYNTHESIS PVT LTD
1Y
Phone:+91-7028392790
Whatsapp: +91 7028392790
product: 2-Bromo-pyrimidine 4595-60-2 98%
CHATURYA BIOTECH
1Y
Phone:+917702707258
Whatsapp: +91 7702707258
product: 4595-60-2 2-Bromopyrimidine 99%
AVIGYABIOSCIENCES PRIVATE LIMITED
1Y
Phone:+91-9849533087
Whatsapp: +91-9849533087
product: 2-Bromo-pyrimidine 98%
New Products
2,2-diethoxyethanethioamide (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin G Tubulysin I 4,4-DIFLUOROCYCLOHEXANAMINE 2,2-Difluoropropylamine hydrochloride 4-(Benzyloxy)-3-bromophenylacetic Acid 1-(1,1-Difluoroethyl)-2-fluorobenzene Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- 2H-Pyran, 4-ethynyltetrahydro- Calcium Sodium Phosphosilicate IH Fuel shell Imeglimin Hydrochloride IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Latanoprostene Bunod Lubiprostone Magnesium Trisilicate Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
You may like
-
4595-60-2 2-Bromopyrimidine 98%View Details
4595-60-2 -
2-Bromopyrimidine 99%View Details
4595-60-2 -
2-Bromopyrimidine 4595-60-2 99%View Details
4595-60-2 -
4595-60-2 2-Bromopyrimidine 99%View Details
4595-60-2 -
2-Bromo-pyrimidine 98%View Details -
2-Bromopyrimidine, 97% CAS 4595-60-2View Details
4595-60-2 -
2-Bromopyrimidine CAS 4595-60-2View Details
4595-60-2 -
2-Bromopyrimidine CAS 4595-60-2View Details
4595-60-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.