Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list2-Bromopyrimidine

2-Bromopyrimidine

  • CAS NO.:4595-60-2
  • Empirical Formula: C4H3BrN2
  • Molecular Weight: 158.98
  • MDL number: MFCD00014601
  • EINECS: 224-993-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:15:30
2-Bromopyrimidine Structural

What is 2-Bromopyrimidine?

Chemical properties

Off-white crystalline powder

The Uses of 2-Bromopyrimidine

2-Bromopyrimidine is used in the preparation of 2,7-bis(2-pyrimidyl)-9,9-dihexylfluorene by cross-coupling with 9,9-dihexylfluorene-2,7-diboronic acid. It undergoes microwave-assisted aminocarbonylation at C-2 with palladium and molybdenum hexacarbonyl.

Preparation

The recent synthesis of 2-bromopyrimidine by diazotization of 2-aminopyrimidine in hydrobromic acid has furnished a convenient starting material for other 2-substituted pyrimidines.

General Description

2-Bromopyrimidine undergoes microwave-assisited aminocarbonylation at C-2 with palladium and Mo(CO)6.

Properties of 2-Bromopyrimidine

Melting point: 55-57 °C (lit.)
Boiling point: 62-64°C (1.5 mmHg)
Density  1.6448 (rough estimate)
refractive index  1.5260 (estimate)
Flash point: 62-64°C/1.5mm
storage temp.  -20°C
solubility  DMSO (Sparingly), Methanol (Slightly)
pka -1.59±0.13(Predicted)
form  Crystalline Powder
color  Off-white
Water Solubility  Miscible with water.
BRN  605945
CAS DataBase Reference 4595-60-2(CAS DataBase Reference)
NIST Chemistry Reference Pyrimidine, 2-bromo-(4595-60-2)
EPA Substance Registry System Pyrimidine, 2-bromo- (4595-60-2)

Safety information for 2-Bromopyrimidine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Bromopyrimidine

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.