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HomeProduct name list2-Bromopyridine-5-boronic acid

2-Bromopyridine-5-boronic acid

Synonym(s):2-Bromopyridine-5-boronic acid

  • CAS NO.:223463-14-7
  • Empirical Formula: C5H5BBrNO2
  • Molecular Weight: 201.81
  • MDL number: MFCD03411558
  • EINECS: 672-028-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-18 11:31:13
2-Bromopyridine-5-boronic acid Structural

What is 2-Bromopyridine-5-boronic acid?

Chemical properties

Off-white solid

The Uses of 2-Bromopyridine-5-boronic acid

Reactant involved in:

  • Iterative cross-coupling reactions for synthesis of non-cytotoxic terpyridines
  • The Garlanding approach for synthesis of phenyl-pyridyl scaffolds
  • Cyanation for synthesis of aromatic nitriles
  • Suzuki-Miyaura cross-coupling with dihalopyridines and dihalobipyridines
  • Petasis boronic Mannich reaction

General Description

May contain varying amounts of anhydride

Properties of 2-Bromopyridine-5-boronic acid

Melting point: 161-166 °C
Boiling point: 358.2±52.0 °C(Predicted)
Density  1.78±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  soluble in Methanol
form  solid
pka 6.62±0.10(Predicted)
color  white to off-white
BRN  9119918
CAS DataBase Reference 223463-14-7(CAS DataBase Reference)

Safety information for 2-Bromopyridine-5-boronic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for 2-Bromopyridine-5-boronic acid

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