3-Hydroxypyridine
Synonym(s):3-Pyridinol;3-Pyridone
- CAS NO.:109-00-2
- Empirical Formula: C5H5NO
- Molecular Weight: 95.1
- MDL number: MFCD00006378
- EINECS: 203-637-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-19 17:35:41
What is 3-Hydroxypyridine?
Chemical properties
white to light yellow crystal. Soluble in alcohol and water, slightly soluble in ether and benzene. It becomes a red solution when it encounters ferric chloride, and it is easy to decompose in the air.
The Uses of 3-Hydroxypyridine
3-Hydroxypyridine (cas# 109-00-2) is a compound useful in organic synthesis.
Definition
ChEBI: 3-Hydroxypyridine is a monohydroxypyridine that is pyridine in which the hydrogen at position 3 has been replaced by a hydroxy group. It has been detected as a thermal degradation product from the smoke of the burning leaves of Salvia divinorum, a Mexican psychoactive plant.
Preparation
3-hydroxypyridine was prepared by reacting furfurylamine with H2O2 in the presence of HCl, followed by hydrolysis. The optimal conditions were found as fellows: molar ratio of furfurylamine: HCl : H2O2 = 1 : 5 : 1.1, and H2O2 added dropwisely at 0-5 °C, and then refluxed at 100-105 °C for 0.5 h.
brand name
Ventavis (Schering).
Purification Methods
Crystallise 3-hydroxypyridine from *C6H6, water or EtOH. [Beilstein 21 III/IV 402, 21/2 V 68.]
Properties of 3-Hydroxypyridine
Melting point: | 125-128 °C (lit.) |
Boiling point: | 280-281 °C(lit.) |
Density | 1.1418 (rough estimate) |
refractive index | 1.5939 (estimate) |
Flash point: | 173°C |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | 33g/l |
form | Crystalline Powder |
pka | 4.79, 8.75(at 20℃) |
color | Beige to brown |
PH | 6.0-6.5 (33g/l, H2O, 20℃) |
Water Solubility | 32.26g/L(20 ºC) |
BRN | 105699 |
CAS DataBase Reference | 109-00-2(CAS DataBase Reference) |
NIST Chemistry Reference | 3-Pyridinol(109-00-2) |
EPA Substance Registry System | 3-Pyridinol (109-00-2) |
Safety information for 3-Hydroxypyridine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Hydroxypyridine
Abamectin manufacturer
ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED
VGS SYNTHESIS PRIVATE LIMITED
SNECOFRi PVT LTD
Lorven therapeutics Pvt Ltd
Sintilla Medcoms Pvt Ltd
Rivashaa Agrotech Biopharma Pvt. Ltd.
New Products
(R)-(-)-2-Amino-1-propanol Tetrahydro-4H-pyran-4-one Bromine 99.5% AR (4 x 500ml) Linseed Oil Extrapure Hydrogen Sulphide Solution Oxalic Acid 0.05 mol/L (0.01N) Solution EDTA 0.1 mol/L (0.2N) for 1000 ml Ferroin 0.025M Solution AR 1,2,3,4-Tetrahydrocarbazol-4-one 4-Hydroxy Carbazole Amino Salicylic Acid. U.S.P. 2 – Methoxy – 5- Sulfamoyl Benzoic acid Acetone Isobutryl oxime ester Sodium Amino Salicylate Dihydrate (PAS Sodium) IP/BP/USP/EP Aloe vera extract 200x Withania somnifera (Ashwagandha Extract) Citrus bioflavonoids Extract Spirulina (Arthrospira platensis) Powder Trikatu Extract Thymol Oil Ethyl 3-(Pyridin-2-Ylamino)Propanoate Bilastine -IP/BP/ Cypermethric Acid Chloride 5-NitrosalicylaldehydeRelated products of tetrahydrofuran
You may like
-
3 - Hydroxypyridine 98%View Details
109-00-2 -
3-Hydroxypyridine 109-00-2 98%View Details
109-00-2 -
3-Hydroxypyridine pure CAS 109-00-2View Details
109-00-2 -
3-Hydroxy pyridine CAS 109-00-2View Details
109-00-2 -
3-Hydroxypyridine CAS 109-00-2View Details
109-00-2 -
3-Hydroxypyridine 98%View Details
-
3-Hydroxypyridine CAS 109-00-2View Details
109-00-2 -
3-Hydroxypyridine CAS 109-00-2View Details
109-00-2