2-Chloro-3-hydroxypyridine
Synonym(s):2-Chloro-3-pyridinol
- CAS NO.：6636-78-8
- Empirical Formula: C5H4ClNO
- Molecular Weight: 129.54
- MDL number: MFCD00006235
- EINECS: 229-635-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-21 15:02:05
What is 2-Chloro-3-hydroxypyridine?
Chemical properties
light beige powder
The Uses of 2-Chloro-3-hydroxypyridine
2-Chloro-3-hydroxypyridine has been used in the preparation of 3-hydroxypyridine-2( 1 H)-selone. It has also been used in the synthesis of all four possible benzo[4,5]furopyridine tricyclic heterocycles: benzo[4,5]furo[2,3-b]pyridine, benzo[4,5]furo[2,3-c]pyridine, benzo[4,5]furo[3,2-c]pyridine, and benzo[4,5]furo[3,2-b]pyridine. the synthesis involves α and γ-activation of chloropyridines, as well as palladium-mediated reactions.
Properties of 2-Chloro-3-hydroxypyridine
| Melting point: | 170-172 °C (lit.) |
| Boiling point: | 316.2±22.0 °C(Predicted) |
| Density | 1.2309 (rough estimate) |
| refractive index | 1.4510 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | Powder |
| pka | 4.32±0.10(Predicted) |
| color | Light beige |
| BRN | 2216 |
| CAS DataBase Reference | 6636-78-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Chloro-3-pyridinol(6636-78-8) |
Safety information for 2-Chloro-3-hydroxypyridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Chloro-3-hydroxypyridine
| InChIKey | RSOPTYAZDFSMTN-UHFFFAOYSA-N |
2-Chloro-3-hydroxypyridine manufacturer
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Phone:+919850500858
Whatsapp: +91-9850500858
product: 2-Chloro-3-hydroxypyridine 98%
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