1,6-Dibromohexane

Synonym(s):1,6-Dibromohexane;Hexamethylene bromide;Hexamethylene dibromide

CAS NO.：629-03-8
Empirical Formula: C6H12Br2
Molecular Weight: 243.97
MDL number: MFCD00000272
EINECS: 211-067-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-25 16:21:11

What is 1,6-Dibromohexane ?

Chemical properties

colourless or pale yellow liquid. soluble in ethanol, ether, benzene and chloroform, insoluble in water. It is used in the synthesis of the hypotensive drug hexamethonium bromide.

The Uses of 1,6-Dibromohexane

1,6-Dibromohexane is used as a reagent in the synthesis of novel benzo[b]xanthone derivatives which have a potential antitumor activity. It is also used as a cross-linker for the cross-linking of glycuronans.

The Uses of 1,6-Dibromohexane

1,6-Dibromohexane is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are:
Synthesis of solvent processable and conductive polyfluorene ionomers for alkaline fuel cell applications.
Synthesis of cross-linkable regioregular poly(3-(5-hexenyl)thiophene) (P3HNT) for stabilizing the film morphology in polymer photovoltaic cells.
Synthesis of pyrrolo-tetrathiafulvalene molecular bridge (6PTTF6) to study redox switching behavior of single molecules.
Synthesis of water-soluble thermoresponsive polylactides.

Preparation

1,6-Dibromohexane is synthesized from hexanediol by bromination.

Properties of 1,6-Dibromohexane

Melting point:	-2-2.5 °C (lit.)
Boiling point:	243 °C (lit.)
Density	1.586 g/mL at 25 °C (lit.)
vapor pressure	<1 hPa (20 °C)
refractive index	n20/D 1.507(lit.)
Flash point:	110 °C
storage temp.	Store below +30°C.
solubility	soluble in Chloroform, Ethyl Acetate
form	Liquid
color	colorless to brownish-yellow
Water Solubility	insoluble
BRN	1236322
Dielectric constant	8.8900000000000006
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	629-03-8(CAS DataBase Reference)
NIST Chemistry Reference	Hexane, 1,6-dibromo-(629-03-8)
EPA Substance Registry System	Hexane, 1,6-dibromo- (629-03-8)

Safety information for 1,6-Dibromohexane

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H317:Sensitisation, Skin H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water.