1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Synonym(s):PC;DLPC;PC(12:0/12:0);(7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxododecyl)oxy]-3,5,9-trioxa-4-phosphaheneicosan-1-aminium 4-oxide, inner salt;L-β,γ-Dilauroyl-α-lecithin

CAS NO.：18194-25-7
Empirical Formula: C32H64NO8P
Molecular Weight: 621.83
MDL number: MFCD00066561
EINECS: 242-086-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 23:02:33

1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE Structural

What is 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE?

Description

DLPC, also known as 1,2-dilauroyl-sn-glycero-3-phosphocholine, is a phospholipid containing the 12 carbon fatty acid/lauric acid (12:0) at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. Due to the medium size of fatty acid chain, DLPC is used to form thinner membranes or lipid bilayers.

The Uses of 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1,2-Dilauroyl-sn-glycero-3-phosphocholine (DLPC) is a phospholipid containing the medium-chain (12:0) lauric acid inserted at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. Experimentally, DLPC is used to form thinner membranes than those produced with PC containing the more common long-chain or very long-chain fatty acids, or to simply vary membrane formulation.

The Uses of 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE

L-α-Dilauroyl Phosphatidylcholine forms robust and versatile membrane bilayers to study the selective and ATP-driven transport ions across membranes into nanoporous carriers using gramicidin A and ATP synthase.

What are the applications of Application

1,2-Dilauroyl-sn-glycero-3-phosphocholine is a useful phospholipid for biological research purposes

Definition

ChEBI: A phosphatidylcholine 24:0 in which the acyl groups at positions 1 and 2 are specified as lauroyl (dodecanoyl).

Properties of 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Melting point:	-1 °C
storage temp.	−20°C
solubility	Soluble to 100 mM in ethanol
form	White to off-white solid.
color	White to off-white
BRN	5676925

Safety information for 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Signal word	Danger
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H360:Reproductive toxicity
Precautionary Statement Codes	P201:Obtain special instructions before use. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention.