1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Synonym(s):PC;DLPC;PC(12:0/12:0);(7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxododecyl)oxy]-3,5,9-trioxa-4-phosphaheneicosan-1-aminium 4-oxide, inner salt;L -β,γ-Dilauroyl-α-lecithin
- CAS NO.：18194-25-7
- Empirical Formula: C32H64NO8P
- Molecular Weight: 621.83
- MDL number: MFCD00066561
- EINECS: 242-086-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE?
Description
DLPC, also known as 1,2-dilauroyl-sn-glycero-3-phosphocholine, is a phospholipid containing the 12 carbon fatty acid/lauric acid (12:0) at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. Due to the medium size of fatty acid chain, DLPC is used to form thinner membranes or lipid bilayers.
The Uses of 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-Dilauroyl-sn-glycero-3-phosphocholine (DLPC) is a phospholipid containing the medium-chain (12:0) lauric acid inserted at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. Experimentally, DLPC is used to form thinner membranes than those produced with PC containing the more common long-chain or very long-chain fatty acids, or to simply vary membrane formulation.
The Uses of 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE
L-α-Dilauroyl Phosphatidylcholine forms robust and versatile membrane bilayers to study the selective and ATP-driven transport ions across membranes into nanoporous carriers using gramicidin A and ATP synthase.
What are the applications of Application
1,2-Dilauroyl-sn-glycero-3-phosphocholine is a useful phospholipid for biological research purposes
Definition
ChEBI: A phosphatidylcholine 24:0 in which the acyl groups at positions 1 and 2 are specified as lauroyl (dodecanoyl).
Properties of 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE
| Melting point: | -1 °C |
| storage temp. | −20°C |
| solubility | Soluble to 100 mM in ethanol |
| form | White to off-white solid. |
| color | White to off-white |
| BRN | 5676925 |
Safety information for 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE
| Signal word | Danger |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H360:Reproductive toxicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHOCHOLINE
| InChIKey | IJFVSSZAOYLHEE-SSEXGKCCSA-N |
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