1,2-Distearoyl-sn-glycero-3-phosphocholine
Synonym(s):PC;DSPC;PC(18:0/18:0);L -α-Phosphatidylcholine, distearoyl;L -β,γ-Distearoyl-α-lecithin
- CAS NO.：816-94-4
- Empirical Formula: C44H88NO8P
- Molecular Weight: 790.15
- MDL number: MFCD00036905
- EINECS: 212-440-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-14 16:14:43
What is 1,2-Distearoyl-sn-glycero-3-phosphocholine?
Description
1,2-Distearoyl-sn-glycero-3-PC (DSPC) is a phospholipid containing the saturated long-chain (18:0) stearic acid inserted at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
The Uses of 1,2-Distearoyl-sn-glycero-3-phosphocholine
18:0 PC (DSPC) has been used:
- in the microbubble monolayer preparation for biomolecule delivery studies into protoplasts
- in the preparation of liposomes for immobilization studies
- in the generation of porphyrin-phospholipid (PoP) liposomes for irinotecan (IRT) and doxorubicin delivery
What are the applications of Application
1,2-Distearoyl-sn-glycero-3-phosphocholine is used to produce non-pyrogenic liposome capable of caging molecules
Properties of 1,2-Distearoyl-sn-glycero-3-phosphocholine
| Melting point: | 236°C(lit.) |
| storage temp. | -20°C |
| solubility | slightly sol. in Chloroform |
| form | powder to crystal |
| color | White to Almost white |
Safety information for 1,2-Distearoyl-sn-glycero-3-phosphocholine
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 1,2-Distearoyl-sn-glycero-3-phosphocholine
| InChIKey | NRJAVPSFFCBXDT-HUESYALOSA-N |
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