10-Hydroxydecanoic acid
Synonym(s):NSC 15139
- CAS NO.：1679-53-4
- Empirical Formula: C10H20O3
- Molecular Weight: 188.26
- MDL number: MFCD00010510
- EINECS: 216-848-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-24 19:19:26
What is 10-Hydroxydecanoic acid?
The Uses of 10-Hydroxydecanoic acid
10-Hydroxydecanoic acid is suitable for use in a study on Novozym 435-catalyzed condensation polymerization of cis-9,10-epoxy-18-hydroxyoctadecanoic acid and its comparison with corresponding polymerization of 10-hydroxydecanoic acid.
The Uses of 10-Hydroxydecanoic acid
Reactant involved in: • ;Synthesis of copolymers of acrylamide and sodium acryloyloxydecanoate1• ;Macrolactonization for preparation of Sansalvamide A2• ;Studies of chain length selectivity for cutinase catalyzed polycondensation reactions3• ;Ruthenium-catalyzed esterification followed by macrocyclization4• ;Synthesis of anhydrides and esters5
Definition
ChEBI: A 10-carbon, omega-hydroxy fatty acid, shown to be the preferred hydroxylation product (together with the 9-OH isomer) of capric acid in biosystems, and used as a standard in lipid assays; reported to have cytotoxic effects.
General Description
10-Hydroxydecanoic acid (10-HDA) is a saturated fatty acid of hydroxy-trans-2-decenoic acid (10H2DA). Its molecule has two functional groups (-OH and -COOH). It has been reported to prevent the lipopolysaccharide-induced NO production in murine macrophages. 10-HDA has been extracted from royal jelly obtained from honeybees (Apis mellifera) and exhibits estrogenic action. Its polymerization with the polyethylene glycol-modified lipase in a transparent benzene solution has been reported to proceed by the formation of ester linkage.
Properties of 10-Hydroxydecanoic acid
| Melting point: | 75-77 °C (lit.) |
| Boiling point: | 330.8±15.0 °C(Predicted) |
| Density | 1.013±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.78±0.10(Predicted) |
| color | White to Off-White |
| CAS DataBase Reference | 1679-53-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 10-Hydroxydecanoic acid(1679-53-4) |
Safety information for 10-Hydroxydecanoic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 10-Hydroxydecanoic acid
| InChIKey | YJCJVMMDTBEITC-UHFFFAOYSA-N |
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