(Z)-Guggulsterone
- CAS NO.:95975-55-6
- Empirical Formula: C21H28O2
- Molecular Weight: 312.45
- MDL number: MFCD01310757
- EINECS: 1308068-626-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is (Z)-Guggulsterone?
The Uses of (Z)-Guggulsterone
Guggulsterone is a broad spectrum steroid receptor ligand. Gum resin of Commiphora mukul marketed as an antihyperlipidemic drug.
What are the applications of Application
Guggulsterone is a broad spectrum steroid receptor ligand
Definition
ChEBI: Guggulsterone is a 3-hydroxy steroid. It has a role as an androgen.
Biological Activity
Broad spectrum steroid receptor ligand; binds with high affinity to mineralocorticoid receptors (K i = 39 nM) and lower affinity to progesterone, androgen and glucocorticoid receptors (K i values are 201, 240 and 224 nM respectively). Functions primarily as an antagonist of these receptors, with the exception of the progesterone receptor where it displays partial agonist effects. Also exerts hypolipidemic activity, likely via antagonism of the receptor for bile acids (farnesoid X receptor; FXR).
Properties of (Z)-Guggulsterone
Boiling point: | 463.3±45.0 °C(Predicted) |
Density | 1.10±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO: 5 mg/mL |
form | powder |
color | light yellow |
CAS DataBase Reference | 95975-55-6(CAS DataBase Reference) |
Safety information for (Z)-Guggulsterone
Computed Descriptors for (Z)-Guggulsterone
Abamectin manufacturer
Apollo ingredients Pvt Ltd
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
You may like
-
95975-55-6 Guggulsterone 99%View Details
95975-55-6 -
1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%View Details
99903-60-3 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%View Details
1805639-70-6 -
1784294-80-9 98%View Details
1784294-80-9 -
Lithium ClavulanateView Details
61177-44-4