Androsterone
Synonym(s):3α-Hydroxy-5α-androstan-17-one;5α-Androstan-3α-ol-17-one
- CAS NO.：53-41-8
- Empirical Formula: C19H30O2
- Molecular Weight: 290.44
- MDL number: MFCD00003618
- EINECS: 200-173-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-09-24 16:40:18
What is Androsterone?
Chemical properties
white to light beige crystalline powder
The Uses of Androsterone
It was isolated from male urine after removed of the phenolic estrogen fraction.
The Uses of Androsterone
Antihypertensor
The Uses of Androsterone
Typical urinary 17-oxosteroid, formed by the metabolic reduction of testosterone. Less potent than testosterone.
Definition
ChEBI: An androstanoid that is 5alpha-androstane having a hydroxy substituent at the 3alpha-position and an oxo group at the 17-position. It is a metabolite of dehydroepiandrosterone .
Purification Methods
Crystallise androsterone from Me2CO/Et2O or Me2CO and sublime it in high vacuum. The acetate [1164-95-0] crystallises from Et2O, Me2CO/Et2O or aqueous EtOH and sublimes in high vacuum with m 165-166o, [] D 25 +87o (c 2, EtOH). [Ruzicka Helv Chim Acta 17 1389 1934, Marker J Am Chem Soc 57 1755 1935, Gnds & Orr J Chem Soc Chem Commun 1239 1982, Beilstein 8 IV 462.]
Properties of Androsterone
| Melting point: | 181-184 °C(lit.) |
| Boiling point: | 372.52°C (rough estimate) |
| alpha | 96 º (c=1, C2H5OH) |
| Density | 1.0320 (rough estimate) |
| refractive index | 1.4709 (estimate) |
| storage temp. | −20°C |
| solubility | Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml |
| pka | 15.14±0.60(Predicted) |
| form | neat |
| Water Solubility | 11.5mg/L(23.5 ºC) |
| Merck | 13,645 |
| BRN | 2217626 |
| CAS DataBase Reference | 53-41-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Androsterone(53-41-8) |
| EPA Substance Registry System | Androsterone (53-41-8) |
Safety information for Androsterone
| Signal word | Danger |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H351:Carcinogenicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for Androsterone
New Products
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![Androsterone-[d4] Glucuronide Sodium Salt](https://img.chemicalbook.in/)
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