Androsterone

Synonym(s):3α-Hydroxy-5α-androstan-17-one;5α-Androstan-3α-ol-17-one

CAS NO.：53-41-8
Empirical Formula: C19H30O2
Molecular Weight: 290.44
MDL number: MFCD00003618
EINECS: 200-173-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-09-24 16:40:18

What is Androsterone?

Chemical properties

white to light beige crystalline powder

The Uses of Androsterone

It was isolated from male urine after removed of the phenolic estrogen fraction.

The Uses of Androsterone

Antihypertensor

The Uses of Androsterone

Typical urinary 17-oxosteroid, formed by the metabolic reduction of testosterone. Less potent than testosterone.

Definition

ChEBI: An androstanoid that is 5alpha-androstane having a hydroxy substituent at the 3alpha-position and an oxo group at the 17-position. It is a metabolite of dehydroepiandrosterone .

Purification Methods

Crystallise androsterone from Me2CO/Et2O or Me2CO and sublime it in high vacuum. The acetate [1164-95-0] crystallises from Et2O, Me2CO/Et2O or aqueous EtOH and sublimes in high vacuum with m 165-166o, [] D 25 +87o (c 2, EtOH). [Ruzicka Helv Chim Acta 17 1389 1934, Marker J Am Chem Soc 57 1755 1935, Gnds & Orr J Chem Soc Chem Commun 1239 1982, Beilstein 8 IV 462.]

Properties of Androsterone

Melting point:	181-184 °C(lit.)
Boiling point:	372.52°C (rough estimate)
alpha	96 º (c=1, C2H5OH)
Density	1.0320 (rough estimate)
refractive index	1.4709 (estimate)
storage temp.	−20°C
solubility	Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
pka	15.14±0.60(Predicted)
form	neat
Water Solubility	11.5mg/L(23.5 ºC)
Merck	13,645
BRN	2217626
CAS DataBase Reference	53-41-8(CAS DataBase Reference)
NIST Chemistry Reference	Androsterone(53-41-8)
EPA Substance Registry System	Androsterone (53-41-8)

Safety information for Androsterone

Signal word	Danger
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H351:Carcinogenicity
Precautionary Statement Codes	P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..…