XL147
- CAS NO.：956958-53-5
- Empirical Formula: C21H16N6O2S2
- Molecular Weight: 448.52
- MDL number: MFCD16621245
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:54:57
What is XL147?
Description
XL147 analog is an analog of XL147 .
The Uses of XL147
XL147 analogue is one of Pyrimidine derivatives as JAK-2 inhibitors in combination with other agents and their use in the treatment of diseases.
What are the applications of Application
XL-147 derivative 2 is an ATP-competetive class I PI3K inhibitor
Definition
ChEBI: XL147 is a sulfonamide that is the N-4-toluenesulfonyl (N-tosyl) derivative of N-(2,1,3-benzothiadiazol-5-yl)quinoxaline-2,3-diamine. A selective PI3K inhibitor used in cancer treatment. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor and an antineoplastic agent. It is a sulfonamide, a quinoxaline derivative, a benzothiadiazole and an aromatic amine.
Properties of XL147
| Boiling point: | 638.9±65.0 °C(Predicted) |
| Density | 1.538 |
| storage temp. | Store at -20°C |
| solubility | ≥22.45 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH |
| form | solid |
| pka | 6.71±0.30(Predicted) |
| color | Light brown to brown |
Safety information for XL147
Computed Descriptors for XL147
New Products
Tubulysin H Tubulysin G 2H-Pyran, 4-ethynyltetrahydro- 2,2-Difluoropropylamine hydrochloride CYCLOBUTYLAMINE HYDROCHLORIDE 1-(1,1-Difluoroethyl)-2-fluorobenzene tetrahydro-4-methyl-2H-pyran 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) Fuel shell (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Imeglimin Hydrochloride IH Calcium Sodium Phosphosilicate IH Magnesium Trisilicate Lubiprostone Latanoprostene Bunod Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 7-Methoxyquinoline-4-carbonitrile 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acid (2R,3S)-2-Azido-3-methylpentanoic acidRelated products of tetrahydrofuran
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