Triethylamine hydrochloride
Synonym(s):Triethylamine hydrochloride;Triethylammonium chloride
- CAS NO.:554-68-7
- Empirical Formula: C6H16ClN
- Molecular Weight: 137.65
- MDL number: MFCD00012500
- EINECS: 209-067-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-13 11:39:26
What is Triethylamine hydrochloride?
Chemical properties
White to off-white crystalline powder
The Uses of Triethylamine hydrochloride
Triethylamine Hydrochloride is a hydrochloride salt of triethyllamine (T775740). Triethylamine is used as a competing base for the separation of acidic basic and neutral drugs by reverse-phased high-performance liquid chromatography (HPLC). Triethylamine induces visual disturbances (such as foggy vision) in humans, and is also used in industry as a quenching agent in the ozonolysis of alkenes (e.g. (E)-2-Pentene [P227315]). Triethylamine is used in the purification of drugs which are pharmacologically or chemically similar through separation in reverse-phase HPLC (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.
Hazard
Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Targets the central nervous system, liver, kidneys, and heart. Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. Harmful if ingested or inhaled. Minimize exposure to this material. Severe overexposure can result in injury or death.
Safety Profile
Moderately toxic by subcutaneousroute. When heated to decomposition it emits toxicvapors of NOx, HCl, and Clí.
Solubility in organics
Soluble in ethanol, chloroform, and alcohol. Insoluble in ether.
Purification Methods
Purify it like the bromide above. [Beilstein 4 IV 327.]
Properties of Triethylamine hydrochloride
Melting point: | 261 °C (dec.)(lit.) |
Boiling point: | 223.18°C (rough estimate) |
Density | 1.07 |
refractive index | 1.4530 (estimate) |
storage temp. | Store below +30°C. |
solubility | 1440 g/L (20°C) |
form | Crystalline Powder |
color | White to off-white |
PH | 5 (10g/l, H2O, 20℃) |
Water Solubility | 1440 g/L (20 ºC) |
Sensitive | Hygroscopic |
Merck | 14,9666 |
BRN | 3906409 |
CAS DataBase Reference | 554-68-7(CAS DataBase Reference) |
EPA Substance Registry System | Ethanamine, N,N-diethyl-, hydrochloride (554-68-7) |
Safety information for Triethylamine hydrochloride
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Triethylamine hydrochloride
InChIKey | ILWRPSCZWQJDMK-UHFFFAOYSA-N |
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