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HomeProduct name listTriethylamine hydrochloride

Triethylamine hydrochloride

Synonym(s):Triethylamine hydrochloride;Triethylammonium chloride

  • CAS NO.:554-68-7
  • Empirical Formula: C6H16ClN
  • Molecular Weight: 137.65
  • MDL number: MFCD00012500
  • EINECS: 209-067-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-13 11:39:26
Triethylamine hydrochloride Structural

What is Triethylamine hydrochloride?

Chemical properties

White to off-white crystalline powder

The Uses of Triethylamine hydrochloride

Triethylamine Hydrochloride is a hydrochloride salt of triethyllamine (T775740). Triethylamine is used as a competing base for the separation of acidic basic and neutral drugs by reverse-phased high-performance liquid chromatography (HPLC). Triethylamine induces visual disturbances (such as foggy vision) in humans, and is also used in industry as a quenching agent in the ozonolysis of alkenes (e.g. (E)-2-Pentene [P227315]). Triethylamine is used in the purification of drugs which are pharmacologically or chemically similar through separation in reverse-phase HPLC (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.

Hazard

Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Targets the central nervous system, liver, kidneys, and heart. Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. Harmful if ingested or inhaled. Minimize exposure to this material. Severe overexposure can result in injury or death.

Safety Profile

Moderately toxic by subcutaneousroute. When heated to decomposition it emits toxicvapors of NOx, HCl, and Clí.

Solubility in organics

Soluble in ethanol, chloroform, and alcohol. Insoluble in ether.

Purification Methods

Purify it like the bromide above. [Beilstein 4 IV 327.]

Properties of Triethylamine hydrochloride

Melting point: 261 °C (dec.)(lit.)
Boiling point: 223.18°C (rough estimate)
Density  1.07
refractive index  1.4530 (estimate)
storage temp.  Store below +30°C.
solubility  1440 g/L (20°C)
form  Crystalline Powder
color  White to off-white
PH 5 (10g/l, H2O, 20℃)
Water Solubility  1440 g/L (20 ºC)
Sensitive  Hygroscopic
Merck  14,9666
BRN  3906409
CAS DataBase Reference 554-68-7(CAS DataBase Reference)
EPA Substance Registry System Ethanamine, N,N-diethyl-, hydrochloride (554-68-7)

Safety information for Triethylamine hydrochloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Triethylamine hydrochloride

InChIKey ILWRPSCZWQJDMK-UHFFFAOYSA-N

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