Triethylamine

Description

Triethylamine (TEA) is a very commonly used organic base. Diisopropylethylamine (DIEA) is a closely related organic base. DIEA is more sterically hindered than TEA therefore is less prone to quaternization when used with highly reactive alkylation agents. TEA has a boiling point of 89 C, making it easier to remove via rotovap distillation. DIEA has a boiling point of 127 C, making it more useful for reactions that are over 90 C. In most situations TEA and DIEA can be used interchangably. However, for certain situations one is a better choice than the other.

The Uses of Triethylamine

Triethylamine is a base used to prepare esters and amides from acyl chlorides as well as in the synthesis of quaternary ammonium compounds. It acts as a catalyst in the formation of urethane foams and epoxy resins, dehydrohalogeantion reactions, acid neutralizers for condensation reactions and Swern oxidations. It finds application in reverse phase high-performance liquid chromatography (HPLC) as a mobile-phase modifier. It is also used as an accelerator activator for rubber, as a propellant, as a corrosion inhibitor, as a curing and hardening agent for polymers and for the desalination of seawater. Furthermore, it is used in the automotive casting industry and the textile industry.

What are the applications of Application

Triethylamine is an amine commonly used in many synthesis pathways