TIQ-A

CAS NO.：420849-22-5
Empirical Formula: C11H7NOS
Molecular Weight: 201.24
MDL number: MFCD06407947
SAFETY DATA SHEET (SDS)
Update Date: 2024-07-02 08:55:01

What is TIQ-A?

Chemical properties

Dark Brown Solid

The Uses of TIQ-A

A cell permeable, potent PARP inhibitor with an IC50 of 450nM. Shown to be neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells ( IC50 of 150nM) and in vivi in rat transient focal ischemia model (3 mg/kg ip).

The Uses of TIQ-A

A cell permeable, potent PARP inhibitor with an IC50 of 450nM. Shown to be neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells ( IC50 of 150nM) and i n vivi in rat transient focal ischemia model (3 mg/kg ip).

What are the applications of Application

TIQ-A is an inhibitor of poly(ADP-ribose) polyerase-1 (PARP-1)

Properties of TIQ-A

Melting point:	256-258°C
Boiling point:	282.2±9.0 °C(Predicted)
Density	1.358±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: 16 mg/mL, soluble
pka	13.04±0.20(Predicted)
form	solid
color	Light green to green

Safety information for TIQ-A

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H312:Acute toxicity,dermal H332:Acute toxicity,inhalation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection.