Tetramethyl-1,3-diaminopropane
Synonym(s):1,3-Bis(dimethylamino)propane;TMPDA
- CAS NO.:110-95-2
- Empirical Formula: C7H18N2
- Molecular Weight: 130.23
- MDL number: MFCD00008337
- EINECS: 203-818-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02

What is Tetramethyl-1,3-diaminopropane?
Description
Tetramethyl-1,3-diaminopropane can be made by methylation of 1,3-diaminopropane with formaldehyde or from dimethylaminopropionitrile and dimethylamine and is an intermediate for corrosion inhibitors, textile auxiliaries, flotation agents, and emulgators. It is also employed as a catalyst for polyurethanes and as a hardener for epoxy resins.
Chemical properties
colourless liquid
General Description
N,N,N′,N′-Tetramethyl-1,3-propanediamine is an acyclic tertiary amine. It shows the ability to absorb CO2 when dissolved in aqueous solution.
N,N,N′,N′-Tetramethyl-1,3-propanediamine (TMPDA) may be used:
As a catalyst for the Baylis-Hillman reaction of cycloalkenones.
In the preparation of homodimeric asymmetric monomethine cyanine dyes during the bisquaternization process.
As a ligand (L) for the preparation of dinuclear μ-carbonato-dicopper(II) species.
Flammability and Explosibility
Flammable
Properties of Tetramethyl-1,3-diaminopropane
Melting point: | 28.9°C (estimate) |
Boiling point: | 145-146 °C(lit.) |
Density | 0.779 g/mL at 25 °C(lit.) |
vapor pressure | 760 mm Hg ( 145 °C) |
refractive index | n |
Flash point: | 89 °F |
storage temp. | Inert atmosphere,Room Temperature |
form | Liquid |
pka | 9.88±0.28(Predicted) |
color | Clear colorless to light yellow |
PH | 12.5 (100g/l, H2O, 20℃) |
explosive limit | 2.9-22.5%(V) |
BRN | 1734176 |
Stability: | Stable. Flammable. Incompatible with strong oxidizing agents, acids, acid chlorides, permanganates, carbon dioxide, nitrates, peroxides, nitrites, halogens. |
CAS DataBase Reference | 110-95-2(CAS DataBase Reference) |
NIST Chemistry Reference | 1,3-Propanediamine, N,N,N',N'-tetramethyl-(110-95-2) |
EPA Substance Registry System | 1,3-Propanediamine, N,N,N',N'-tetramethyl- (110-95-2) |
Safety information for Tetramethyl-1,3-diaminopropane
Signal word | Danger |
Pictogram(s) |
![]() Flame Flammables GHS02 ![]() Corrosion Corrosives GHS05 ![]() Skull and Crossbones Acute Toxicity GHS06 ![]() Environment GHS09 |
GHS Hazard Statements |
H226:Flammable liquids H314:Skin corrosion/irritation H331:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H411:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Tetramethyl-1,3-diaminopropane
Tetramethyl-1,3-diaminopropane manufacturer
Cns Chemicals
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