Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list(R)-(-)-alpha-Methoxyphenylacetic acid

(R)-(-)-alpha-Methoxyphenylacetic acid

Synonym(s):O-Methyl-D-mandelic acid

  • CAS NO.:3966-32-3
  • Empirical Formula: C9H10O3
  • Molecular Weight: 166.17
  • MDL number: MFCD00004250
  • EINECS: 223-580-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-25 16:21:11
(R)-(-)-alpha-Methoxyphenylacetic acid Structural

What is (R)-(-)-alpha-Methoxyphenylacetic acid?

Chemical properties

white fine crystalline powder or needles

The Uses of (R)-(-)-alpha-Methoxyphenylacetic acid

(R)-(-)-α-Methoxyphenylacetic Acid is a useful synthetic intermediate. It is used as a reactant in the synthesis of dopamine receptor agonists. It can also be used to prepare hydroxytriamides as potent γ-secretase inhibitors.

General Description

(R)-(?)-α-Methoxyphenylacetic acid is a chiral derivatizating agent, which is employed for derivatizing enantiomers into diastereoisomers.

Purification Methods

Purify the acids by recrystallising from *C6H6/pet ether (b 80-100o). [Neilson & Peters J Chem Soc 1519 1962, Weizmann et al. J Am Chem Soc 70 1153 1948, Pirie & Smith J Chem Soc 338 1932, NMR: Dale & Mosher J Am Chem Soc 9 5 512 1973, for resolution: Roy & Deslongchamps Can J Chem 63 651 1985, Trost et al. J Am Chem Soc 1 0 8 4974 1986.] The racemic mixture has m 72o, b 121-122o/0.4mm, 165o/18mm (from pet ether) [Braun et al. Chem Ber 6 3 2847 1930]. [Beilstein 10 IV 566.]

Properties of (R)-(-)-alpha-Methoxyphenylacetic acid

Melting point: 66-68 °C(lit.)
Boiling point: 164-166°C 18mm
alpha  -160.4 º (C=1, MEOH)
Density  1.1708 (rough estimate)
refractive index  -147 ° (C=0.5, EtOH)
Flash point: 164-166°C/18mm
storage temp.  2-8°C
solubility  Chloroform, Ethanol, Methanol
form  Fine Crystalline Powder or Needles
pka 3.10±0.10(Predicted)
color  White
optical activity [α]20/D -150±3°, c = 0.5% in ethanol
BRN  3589257
CAS DataBase Reference 3966-32-3(CAS DataBase Reference)
NIST Chemistry Reference (R)-(-)-«alpha»-methoxyphenylacetic acid(3966-32-3)

Safety information for (R)-(-)-alpha-Methoxyphenylacetic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (R)-(-)-alpha-Methoxyphenylacetic acid

Related products of tetrahydrofuran

You may like

  • (R)-(-)-alpha-Methoxyphenylacetic acid CAS 3966-32-3
    (R)-(-)-alpha-Methoxyphenylacetic acid CAS 3966-32-3
    3966-32-3
    View Details
  • (R)-(-)-α-Methoxyphenylacetic Acid CAS 3966-32-3
    (R)-(-)-α-Methoxyphenylacetic Acid CAS 3966-32-3
    3966-32-3
    View Details
  • 1823368-42-8 98%
    1823368-42-8 98%
    1823368-42-8
    View Details
  • 2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    1307449-08-6
    View Details
  • Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    25408-95-1
    View Details
  • 2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    1805639-70-6
    View Details
  • 1784294-80-9 98%
    1784294-80-9 98%
    1784294-80-9
    View Details
  • Lithium Clavulanate
    Lithium Clavulanate
    61177-44-4
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.