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HomeProduct name list(R)-(+)-2-Chloropropionic acid

(R)-(+)-2-Chloropropionic acid

  • CAS NO.:7474-05-7
  • Empirical Formula: C3H5ClO2
  • Molecular Weight: 108.52
  • MDL number: MFCD00064204
  • EINECS: 626-432-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-04 20:04:50
(R)-(+)-2-Chloropropionic acid Structural

What is (R)-(+)-2-Chloropropionic acid?

Chemical properties

Colourless Oil

The Uses of (R)-(+)-2-Chloropropionic acid

(R)-(+)-2-Chloropropionic acid can be used as a starting material in the synthesis of:???????

  • Thiolactic acid, a key intermediate, which is used for the preparation of 2(R),5(S)-oxathiolanones by reacting with pivalaldehyde.???????
  • (R)-2-chloropropionyl chloride, a key intermediate, which is utilized in the synthesis of (R)-4,5-dihydro-5-methylpyridazin-3(2H)-one derivative with pyrazolopyridine ring as a potential phosphodiesterase inhibitor.???????
  • 2-Chloropropionamide derivatives as protein disulfide isomerase (PID) inhibitors.

Properties of (R)-(+)-2-Chloropropionic acid

Melting point: -12°C
Boiling point: 185-188 °C (lit.)
alpha  14 º (neat)
Density  1.258 g/mL at 20 °C (lit.)
refractive index  n20/D 1.4345(lit.)
Flash point: 140 °F
storage temp.  −20°C
solubility  soluble in Chloroform, Methanol
form  clear liquid
pka 2.96±0.10(Predicted)
color  Colorless to Almost colorless
optical activity [α]20/D +14°, neat
BRN  1720258
CAS DataBase Reference 7474-05-7(CAS DataBase Reference)

Safety information for (R)-(+)-2-Chloropropionic acid

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H314:Skin corrosion/irritation
Precautionary Statement Codes P270:Do not eat, drink or smoke when using this product.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (R)-(+)-2-Chloropropionic acid

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