PROSTAGLANDIN B2

Synonym(s):(5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,8(12),13-trien-1-oic acid;PGB₂

CAS NO.：13367-85-6
Empirical Formula: C20H30O4
Molecular Weight: 334.45
MDL number: MFCD00065730
EINECS: 635-050-8
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

What is PROSTAGLANDIN B2?

Description

Prostaglandin B₂ (PGB₂) is a non-enzymatic dehydration product resulting from the treatment of PGE₂ or PGA₂ (Item Nos. 10210 | 10007199) with strong base. It has weak agonist activity on TP receptors and can increase pulmonary blood pressure in the rabbit at relatively high doses (5 μg/kg).

PGB₂ MaxSpec^® standard is a quantitative grade standard of PGB₂ that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This PGB₂ MaxSpec^® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.

The Uses of PROSTAGLANDIN B2

PGB2 (Prostaglandin B2) is an abundant prostaglandin released from osteoblasts.

What are the applications of Application

PGB2 (Prostaglandin B2) is an abundant prostaglandin released from osteoblasts

Definition

ChEBI: Prostaglandin B2 is a prostaglandins B. It has a role as a human metabolite. It is a conjugate acid of a prostaglandin B2(1-).

Properties of PROSTAGLANDIN B2

Boiling point:	537.0±50.0 °C(Predicted)
Density	1.118±0.06 g/cm3(Predicted)
Flash point:	-9 °C
storage temp.	−20°C
solubility	ethanol: ~100 mg/mL
pka	4.74±0.10(Predicted)
form	solution
color	Colorless to light yellow
BRN	2153006

Safety information for PROSTAGLANDIN B2

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H225:Flammable liquids H319:Serious eye damage/eye irritation H336:Specific target organ toxicity,single exposure; Narcotic effects
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.