CARBACYCLIN
- CAS NO.：69552-46-1
- Empirical Formula: C21H34O4
- Molecular Weight: 350.49
- MDL number: MFCD00210824
- EINECS: 636-209-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:54:58
What is CARBACYCLIN?
The Uses of CARBACYCLIN
Carbacyclin is a stable analog of PGI2. When infused in rabbits or dogs, it inhibits ex vivo platelet aggregation, but the effect persists only 10 minutes after termination of the infusion. Carbacyclin is a stable analog of PGI2. Carbacyclin inhibits platelet aggregation with 10% of the molar potency exhibited by PGI2. The ED50 of Carbacyclin for the in vitro inhibition of ADP-induced platelet aggregation in human PRP is 47 nM. It was also shown to effect terminal differentiation of preadipose into adipose cells and enhance the expression of angiotensinogen and adipose fatty acid binding protein with an EC50 of about 0.5 μM.
The Uses of CARBACYCLIN
Carbacyclin acts as a converter of human white to bright adipocytes. Also used in the treatment of high-risk acute lymphoblastic leukemia potentiating the activity of anti-cancer therapeutics.
What are the applications of Application
Carbacyclin (Carbocyclic PGI2) is a stable analog of prostacyclin that inhibits platelet aggregation
Definition
ChEBI: Carbaprostacyclin is a prostanoid.
Properties of CARBACYCLIN
| Melting point: | 65-67℃ |
| Boiling point: | 514.8±50.0 °C(Predicted) |
| Density | 1.177±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | Soluble at 20mg/ml in ethanol. |
| form | Solid |
| pka | 4.77±0.10(Predicted) |
| color | White to off-white |
Safety information for CARBACYCLIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H332:Acute toxicity,inhalation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P321:Specific treatment (see … on this label). P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
Computed Descriptors for CARBACYCLIN
New Products
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