CARBACYCLIN

CAS NO.：69552-46-1
Empirical Formula: C21H34O4
Molecular Weight: 350.49
MDL number: MFCD00210824
EINECS: 636-209-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

What is CARBACYCLIN?

The Uses of CARBACYCLIN

Carbacyclin is a stable analog of PGI2. When infused in rabbits or dogs, it inhibits ex vivo platelet aggregation, but the effect persists only 10 minutes after termination of the infusion. Carbacyclin is a stable analog of PGI2. Carbacyclin inhibits platelet aggregation with 10% of the molar potency exhibited by PGI2. The ED50 of Carbacyclin for the in vitro inhibition of ADP-induced platelet aggregation in human PRP is 47 nM. It was also shown to effect terminal differentiation of preadipose into adipose cells and enhance the expression of angiotensinogen and adipose fatty acid binding protein with an EC50 of about 0.5 μM.

The Uses of CARBACYCLIN

Carbacyclin acts as a converter of human white to bright adipocytes. Also used in the treatment of high-risk acute lymphoblastic leukemia potentiating the activity of anti-cancer therapeutics.

What are the applications of Application

Carbacyclin (Carbocyclic PGI2) is a stable analog of prostacyclin that inhibits platelet aggregation

Definition

ChEBI: Carbaprostacyclin is a prostanoid.

Properties of CARBACYCLIN

Melting point:	65-67℃
Boiling point:	514.8±50.0 °C(Predicted)
Density	1.177±0.06 g/cm3(Predicted)
storage temp.	−20°C
solubility	Soluble at 20mg/ml in ethanol.
form	Solid
pka	4.77±0.10(Predicted)
color	White to off-white

Safety information for CARBACYCLIN

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H312:Acute toxicity,dermal H332:Acute toxicity,inhalation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P321:Specific treatment (see … on this label). P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.