PRISTANE

Synonym(s):2,6,10,14-Tetramethylpentadecane

CAS NO.：1921-70-6
Empirical Formula: C19H40
Molecular Weight: 268.52
MDL number: MFCD00008952
EINECS: 217-650-8
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-12 16:52:33

What is PRISTANE?

Chemical properties

colourless liquid

The Uses of PRISTANE

Pristane is a hydrocarbon oil adjuvant.

The Uses of PRISTANE

Lubricant; transformer oil. Anti-corrosion agent. Biological marker. In experimental systems to induce plasmacytomas; in production of monoclonal antibodies.

The Uses of PRISTANE

Pristane has been used as an inflammation-inducing agent, leading to myeloma development in BALB/c strain mice. It has been used as a rheumatoid arthritis-inducing agent in rats.

What are the applications of Application

Pristane is a hydrocarbon oil adjuvant widely used to induce tumorgenesis in mice and arthritis and lupus nephritis in rats.

Definition

ChEBI: A norterpene that is an acyclic saturated hydrocarbon derived from phytane by loss of its C-16 terminal methyl group.

General Description

Pristane is a natural saturated terpenoid alkane used in research on the pathogenesis of autoimmune diseases such as arthritis and lupus.

Biochem/physiol Actions

Pristane is a hydrocarbon oil adjuvant widely used to induce tumorigenesis in mice and arthritis and lupus nephritis in rats. It works as a adjuvant for monoclonal antibody generation in mouse ascites.

Purification Methods

Purify pristane by shaking it with conc H2SO4 (care, if amount of pristane is too small then it should be diluted with pet ether not Et2O which is quite soluble H2SO4), then H2O (care, as it may heat up in contact with conc H2SO4), dry (MgSO4), evaporate and distil it over Na. [S.rensen & S.rensen Acta Chem Scand 3 939 1949, Beilstein 1 III 570.]

Properties of PRISTANE

Melting point:	-99 °C
Boiling point:	68 °C/0.001 mmHg (lit.)
Density	0.783 g/mL at 20 °C (lit.)
refractive index	n20/D 1.438(lit.)
Flash point:	110 °C
storage temp.	Store at -20°C
solubility	DMSO : 100 mg/mL (372.41 mM; Need ultrasonic)
form	liquid
color	Clear colorless
Water Solubility	0.01ug/L(25 ºC)
Merck	14,7752
BRN	1720538
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents.
EPA Substance Registry System	Pristane (1921-70-6)

Safety information for PRISTANE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.