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HomeProduct name listPARAMETHASONE ACETATE (200 MG)

PARAMETHASONE ACETATE (200 MG)

  • CAS NO.:1597-82-6
  • Empirical Formula: C24H31FO6
  • Molecular Weight: 434.4977432
  • MDL number: MFCD00200359
  • EINECS: 2164864
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 20:33:22
PARAMETHASONE ACETATE (200 MG) Structural

What is PARAMETHASONE ACETATE (200 MG)?

Originator

Haldrone,Lilly,US,1961

The Uses of PARAMETHASONE ACETATE (200 MG)

Glucocorticoid.

The Uses of PARAMETHASONE ACETATE (200 MG)

Paramethasone Acetate, is a derivative of Dexamethasone (D298800), a potent synthetic member of the glucocorticoid class of steroid drugs that has anti-inflammatory and immunosuppressant properties.

Definition

ChEBI: Paramethasone acetate is a corticosteroid hormone.

Manufacturing Process

A solution of 0.144 g of the 3-ethylene glycol ketal of 5α,11β,17α,21 tetrahydroxy-6β-fluoro-16α-methylallopregnane-3,20-dione-21 acetate in 12 ml of chloroform and 0.1 ml of absolute alcohol was cooled to -10°C in an icesalt bath and a stream of anhydrous hydrochloric acid was gently bubbled through the solution for 2.5 hours while the temperature was maintained between -5°C and -15°C. The solution was then diluted with 25 ml of chloroform, washed with dilute sodium bicarbonate and water, dried over anhydrous sodium sulfate, and evaporated to dryness under reduced pressure at 60°C or less to give 6α-fluoro-11β,17α,21-trihydroxy-16α-methyl-4-pregnene3,20-dione 21-acetate.

brand name

Haldrone (Lilly).

Therapeutic Function

Glucocorticoid

Safety Profile

Poison by intraperitoneal route. An experimental teratogen. When heated to decomposition it emits toxic fumes of Fí.

Metabolism

Not Available

Properties of PARAMETHASONE ACETATE (200 MG)

Melting point: 228-241° (dec)
Boiling point: 584.2±50.0 °C(Predicted)
alpha  D +85°
Density  1.1517 (estimate)
storage temp.  Refrigerator
solubility  Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 12.29±0.70(Predicted)
color  Crystals from Me2CO/hexane
EPA Substance Registry System Paramethasone acetate (1597-82-6)

Safety information for PARAMETHASONE ACETATE (200 MG)

Computed Descriptors for PARAMETHASONE ACETATE (200 MG)

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