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HomeProduct name listN-Acetyl-L-methionine

N-Acetyl-L-methionine

  • CAS NO.:65-82-7
  • Empirical Formula: C7H13NO3S
  • Molecular Weight: 191.25
  • MDL number: MFCD00064441
  • EINECS: 200-617-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-07 08:52:35
N-Acetyl-L-methionine Structural

What is N-Acetyl-L-methionine?

Chemical properties

white crystals

The Uses of N-Acetyl-L-methionine

N-Acetyl-L-methionine (CAS# 65-82-7) has been useful in the study of metabolic phenotypes of standard and cold-?stored platelets.

Definition

ChEBI: An L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group.

Safety Profile

Poison by intravenous route. When heated to decomposition emits toxic fumes of NOX,.

Purification Methods

Crystallise N-acetyl-L-methionine from Me2CO, H2O or EtOAc. Dry it in a vacuum over P2O5. Its solubility at 25o in H2O is 30.7%, and in Me2CO it is 29.5%. [Mitzi & Schueter Biochim Biophys Acta 27 168 1958, Birnbaum et al. J Biol Chem 194 455 1952, Beilstein 4 IV 3206.]

Properties of N-Acetyl-L-methionine

Melting point: 103-106 °C(lit.)
Boiling point: 235 °C(Press: 12 Torr)
alpha  -20 º (c=4 H2O)
Density  1.2684 (rough estimate)
refractive index  -21 ° (C=1, H2O)
storage temp.  Sealed in dry,Room Temperature
solubility  methanol: soluble100mg/mL, clear, colorless
form  Solid
pka 3.50±0.10(Predicted)
color  White to Off-White
optical activity [α]20/D -21.0±1.0°, c = 1% in H2O
Merck  14,96
BRN  1725552
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 65-82-7(CAS DataBase Reference)
NIST Chemistry Reference N-acetylmethionine(65-82-7)
EPA Substance Registry System L-Methionine, N-acetyl- (65-82-7)

Safety information for N-Acetyl-L-methionine

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.

Computed Descriptors for N-Acetyl-L-methionine

InChIKey XUYPXLNMDZIRQH-LURJTMIESA-N

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