N-(9-Fluorenylmethoxycarbonyloxy)succinimide
Synonym(s):N-(9-Fluorenylmethoxycarbonyloxy)succinimide;9-Fluorenylmethyl N-succinimidyl carbonate;FMOC-ONSu, N-(9H-Fluoren-9-ylmethoxycarbonyloxy)succinimide;Fmoc-OSu;N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 9-Fluorenylmethyl-succinimidyl carbonate
- CAS NO.：82911-69-1
- Empirical Formula: C19H15NO5
- Molecular Weight: 337.33
- MDL number: MFCD00010733
- EINECS: 433-520-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-15 15:41:51
What is N-(9-Fluorenylmethoxycarbonyloxy)succinimide?
Chemical properties
White powder
The Uses of N-(9-Fluorenylmethoxycarbonyloxy)succinimide
N-(9-Fluorenylmethoxycarbonyloxy)succinimide is used in conjunction with Isothiocyanate to conduct partial Edman Degradation on biologically active peptides.
The Uses of N-(9-Fluorenylmethoxycarbonyloxy)succinimide
N-protecting reagent for oligonucleotide and peptide syntheses
The Uses of N-(9-Fluorenylmethoxycarbonyloxy)succinimide
Reagent for the preparation of pure Fmoc amino acids free from contamination by Fmoc-dipeptides.
What are the applications of Application
Fmoc N-hydroxysuccinimide ester is an efficient reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives
Purification Methods
Recrystallise the carbonate from CHCl3/Et2O, or from pet ether (b 40-60o). [Pauet Can J Chem 60 976 1982, Lapatsaris et al. Synthesis 671 1983.]
Properties of N-(9-Fluorenylmethoxycarbonyloxy)succinimide
| Melting point: | 150-153 °C(lit.) |
| Boiling point: | 150-153°C |
| Density | 1.3460 (rough estimate) |
| refractive index | 1.5000 (estimate) |
| storage temp. | 2-8°C |
| solubility | Soluble in dimethyl sulfoxide and dimethyl formamide. |
| form | Microfine Powder |
| color | White or almost white |
| Sensitive | Moisture Sensitive |
| BRN | 3569540 |
| Stability: | Moisture Sensitive |
| CAS DataBase Reference | 82911-69-1(CAS DataBase Reference) |
Safety information for N-(9-Fluorenylmethoxycarbonyloxy)succinimide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H317:Sensitisation, Skin H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for N-(9-Fluorenylmethoxycarbonyloxy)succinimide
N-(9-Fluorenylmethoxycarbonyloxy)succinimide manufacturer
JSK Chemicals
2Y
Phone:+919879767970
Whatsapp: +91 9879767970
product: Fmoc N-hydroxysuccinimide ester, 98% 99%
Anand Agencies
Maharashtra
Phone:91-9075014125
Whatsapp: 91-9075014125
product: N-(9-Fluorenylmethoxycarbonyloxy)succinimide
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