Methylaminoformyl chloride

CAS NO.：6452-47-7
Empirical Formula: C2H4ClNO
Molecular Weight: 93.51
MDL number: MFCD08703300
EINECS: 229-253-7
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is Methylaminoformyl chloride?

The Uses of Methylaminoformyl chloride

Methylcarbamoyl Chloride is used as a reagent in the synthesis of acylprolinamides as a new class of peptide deformylase inhibitors with in vivo antibacterial activity. Methylcarbamoyl Chloride is also used as a reagent in the synthesis of carbamate derivatives as potential dual-binding site acetylcholinesterase inhibitors.

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 1888, 1950 DOI: 10.1021/ja01161a009

Properties of Methylaminoformyl chloride

Melting point:	45°C
Boiling point:	93°C (dec.)
Density	1.185±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Acetonitrile, Chloroform (Slightly), DMSO
form	Solid
pka	10.67±0.46(Predicted)
color	White to Off-White
Stability:	Air Sensitive, Hygroscopic, Moisture Sensitive, Volatile
CAS DataBase Reference	6452-47-7(CAS DataBase Reference)

Safety information for Methylaminoformyl chloride

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..…