4-Chlorobenzoyl chloride

CAS NO.：122-01-0
Empirical Formula: C7H4Cl2O
Molecular Weight: 175.01
MDL number: MFCD00000686
EINECS: 204-515-3
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-22 20:27:16

What is 4-Chlorobenzoyl chloride?

Chemical properties

liquid

The Uses of 4-Chlorobenzoyl chloride

4-Chlorobenzoyl chloride was used to synthesize 4-chlorobenzoyl CoA by reacting it with CoA in KHCO3 buffer. 4-Chlorobenzoyl chloride may be used in the following studies Acylation of benzene using different solid acid catalysts such as dodecatungstophosphoric acid (DTPA), DTPA/K-10 clay, K-10, Amberlite, Amberlyst-15, Indion-130, Filtrol-24 clay and sulfated zirconia, Preparation of 1-(4-chlorobenzoyl)-2, 7-dimethoxynaphthalene, Preparation of 4-chlorobenzoyl CoA, via reaction with CoA in KHCO3 buffer, Preparation of 1-aryloxyacetyl-4-(4-chlorobenzoyl)-semicarbazides.

Definition

ChEBI: An acyl chloride consisting of benzoyl chloride having a chloro substituent in the para-position.

General Description

4-Chlorobenzoyl chloride is an acyl chloride. It reacts with 2-amino-2-seleno-5,5-dimethyl-1,3,2-dioxaphosphorinane to yield the respective N-acyl selenophosphoramides.

Properties of 4-Chlorobenzoyl chloride

Melting point:	11-14 °C (lit.)
Boiling point:	102-104 °C/11 mmHg (lit.)
Density	1.365 g/mL at 20 °C (lit.)
vapor pressure	5.8-73.9Pa at 20-50℃
refractive index	n20/D 1.578(lit.)
Flash point:	221 °F
storage temp.	Store below +30°C.
solubility	soluble in Chloroform, DMSO
form	Liquid
color	Clear colorless to faintly colored
explosive limit	1.5-15%(V)
Water Solubility	Reacts with water. Reacts with alcohol.
FreezingPoint	12~14℃
Sensitive	Moisture Sensitive
BRN	471606
Stability:	Stable. Moisture sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference	122-01-0(CAS DataBase Reference)
NIST Chemistry Reference	4-Chlorobenzoic acid chloride(122-01-0)
EPA Substance Registry System	Benzoyl chloride, 4-chloro- (122-01-0)

Safety information for 4-Chlorobenzoyl chloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.