Masitinib
- CAS NO.:790299-79-5
- Empirical Formula: C28H30N6OS
- Molecular Weight: 498.64
- MDL number: MFCD09954132
- EINECS: 226-164-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-13 12:20:35
What is Masitinib?
Chemical properties
Off-White to Pale Yellow Solid
The Uses of Masitinib
Masitinib is a novel tyrosine kinase inhibitor (TKI) being developed by AB Science to treat symptoms of amyotrophic lateral sclerosis (ALS). Masitinib controlled-release implant for treating solid neoplasm.
What are the applications of Application
Masitinib is A tyrosine kinase, c-Kit, PDGFR, FGFR3, and FAK pathway inhibitor
Definition
ChEBI: Masitinib is a member of the class of benzamides that is the carboxamide resulting from the formal condensation of the carboxy group of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid with the primary amino group of 4-methyl-N(3)-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]benzene-1,3-diamine. It is a highly selective oral tyrosine kinase inhibitor. It has a role as a tyrosine kinase inhibitor, an antineoplastic agent and an antirheumatic drug. It is a N-alkylpiperazine, a member of 1,3-thiazoles, a member of pyridines and a member of benzamides.
Side Effects
Masitinib is relatively well tolerated with the most common side effects being asthenia (loss of strength and/or energy), rash, nausea, oedema (fluid retention) and diarrhoea.
storage
Store at -20°C
Properties of Masitinib
Melting point: | 90-95°C |
Density | 1.280±0.06 g/cm3(Predicted) |
storage temp. | Refrigerator |
solubility | Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 13.24±0.70(Predicted) |
color | Off-White to Pale Beige |
Safety information for Masitinib
Computed Descriptors for Masitinib
Abamectin manufacturer
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