Volitinib
- CAS NO.:1313725-88-0
- Empirical Formula: C17H15N9
- Molecular Weight: 345.36
- MDL number: MFCD28359096
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-09-20 16:43:00
What is Volitinib?
Description
Savolitinib selectively inhibits the MET receptor, blocking the PI3K/AKT/MAPK-signaling pathway as well as downregulating MYC.
The Uses of Volitinib
Savolitinib is a potent and highly selective c-Met inhibitor. Savoltinib demonstrated anti-tumor efficacy in a panel of cMet-dysregulated gastric cancer PDX models. Savolitinib also demonstrated good antitmuor activities.
Clinical Use
It is currently being evaluated in phase I clinical trials in combination with EGFR TKIs in NSCLC patients.
Properties of Volitinib
Melting point: | 205-207°C |
Density | 1.55±0.1 g/cm3(Predicted) |
storage temp. | -20°C Freezer |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | 5.67±0.50(Predicted) |
form | Solid |
color | Pale Beige |
CAS DataBase Reference | 1313725-88-0 |
Safety information for Volitinib
Computed Descriptors for Volitinib
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