koumine
- CAS NO.:1358-76-5
- Empirical Formula: C20H22N2O
- Molecular Weight: 306.4
- MDL number: MFCD11111448
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-07 21:39:59
What is koumine?
Description
The Chinese drug 'Kou-wen', said to be derived from Gelsemium elegans Benth., is stated to contain this alkaloid which forms rhombic prisms from Me2 CO. It has [α]23D - 265° (EtOH) and forms a crystalline hydrochloride, m.p. 255°C (dec.) and a hydrobromide, m.p. 269°C (dec.).
Occurrence
Koumine is an alkaloid isolated from Gelsemium elegans Benth.
The Uses of koumine
Koumine is known to attenuate the lipopolysaccharide-stimulated inflammation in RAW264.7 macrophages.
References
Chou, Pak, Hou., Chin. 1. Physiol., 5, 345 (1931)
Chou, Wang, Chen., ibid, 8,40 (1934)
Chi, Kao, Huang., 1. Amer. Chem. Soc., 60, 1723 (1938)
Properties of koumine
Melting point: | 168℃ |
Boiling point: | 436.5±45.0 °C(Predicted) |
Density | 1.42 |
storage temp. | 2-8°C |
solubility | DMSO : 31.25 mg/mL (101.99 mM; Need ultrasonic) |
form | powder |
pka | 8.67±0.40(Predicted) |
color | Yellow-brown |
Safety information for koumine
Computed Descriptors for koumine
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
Cianidanol
DihydrocurcuMin
Diammonium glycyrrhizinate
Chenodeoxycholic acid
Dihydrokawain
Vincristine
LICOCHALCONE-A
Catharanthine
You may like
-
Koumine CAS 1358-76-5View Details
1358-76-5 -
Dechloro DesloratadineView Details
-
Dehydro DesloratadineView Details
-
Edoxaban Impurity 57View Details
2089454-69-1 -
Eltrombopag N-Oxide ImpurityView Details
2734533-17-4 -
Empagliflozin Bromo ImpurityView Details
-
Glycopyrronium Bromide EP Impurity IView Details
1404617-94-2 -
Ipratropium EP Impurity BView Details
58073-59-9
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.