Catharanthine
Synonym(s):(+)-3,4-Didehydrocoronaridine;(2α,5β,6α,18β)-3,4-Didehydroibogamine-18-carboxylic acid methyl ester;7-Ethyl-9,10,12,13-tetrahydro-6,9-methano-5H-pyrido[1′,2′:1,2]azepino[4,5-b]indole-6(6aH)-carboxylic acid methyl ester
- CAS NO.:2468-21-5
- Empirical Formula: C21H24N2O2
- Molecular Weight: 336.43
- MDL number: MFCD01753356
- EINECS: 219-586-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is Catharanthine?
Chemical properties
Off-White to Pale Beige Solid
The Uses of Catharanthine
Catharanthine is an indole alkaloid analog and an inhibitor of TRPM8.
The Uses of Catharanthine
Precursor of Vinblastine-type alkaloids
The Uses of Catharanthine
Anticancer
What are the applications of Application
Catharanthine base is an alkaloids present in Catharanthus roseus
Definition
ChEBI: Catharanthine is an organic heteropentacyclic compound and monoterpenoid indole alkaloid produced by the medicinal plant Catharanthus roseus via strictosidine. It is a bridged compound, an organic heteropentacyclic compound, a methyl ester, a monoterpenoid indole alkaloid, a tertiary amino compound and an alkaloid ester. It is a conjugate base of a catharanthine(1+).
Properties of Catharanthine
Melting point: | 138-1400C |
Boiling point: | 472.9°C (rough estimate) |
alpha | D27 +29.8° (CHCl3) |
Density | 1.1367 (rough estimate) |
refractive index | 1.6500 (estimate) |
storage temp. | Sealed in dry,Store in freezer, under -20°C |
solubility | DMSO: soluble5mg/mL (clear solution; warmed) |
form | powder |
pka | 6.8(at 25℃) |
color | white to beige |
optical activity | [α]/D +30 to +38° (c=0.5, CDCl3) |
Safety information for Catharanthine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P272:Contaminated work clothing should not be allowed out of the workplace. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Catharanthine
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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