Ixazomib citrate (USAN)
- CAS NO.:1239908-20-3
- Empirical Formula: C20H23BCl2N2O9
- Molecular Weight: 517.12
- MDL number: MFCD29767859
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-12 15:22:14
What is Ixazomib citrate (USAN)?
The Uses of Ixazomib citrate (USAN)
Ixazomib Citrate is a reversible boronic acid proteasome inhibitor.
Definition
ChEBI: A glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of 2,2'-{2-[(1R)-1-amino-3-methylbutyl]-5-oxo-1,3,2-dioxaborolane-4,4-diy }diacetic acid. A prodrug for ixazomib that is used in combination therapy for treatment of multiple myeloma.
Properties of Ixazomib citrate (USAN)
Density | 1.47±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | DMSO:100.0(Max Conc. mg/mL);193.38(Max Conc. mM) Ethanol:100.0(Max Conc. mg/mL);193.38(Max Conc. mM) |
form | Solid |
pka | 3.59±0.10(Predicted) |
color | White to off-white |
Safety information for Ixazomib citrate (USAN)
Computed Descriptors for Ixazomib citrate (USAN)
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
Carfilzomib
Bortezomib
Ibrutinib
Bendamustine
Repaglinide
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
Acetamide, 2-amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-
Ixazomib Impurity 1
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